Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany; TUM-Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.
Eur J Radiol. 2020 Apr;125:108867. doi: 10.1016/j.ejrad.2020.108867. Epub 2020 Feb 7.
To investigate paraspinal muscle characteristics and lumbar bone mineral density (BMD) and their associations in routine abdominal multi-detector computed tomography (MDCT) as well as the impact of osteoporotic vertebral fractures on such associations.
116 patients (69.7 ± 8.1 years, 72 males) who underwent routine abdominal MDCT (oncological staging and/or follow-up for tumor recurrence) were retrospectively included and assigned to a fracture and control group (age- and gender-matched), depending on the presence or absence of lumbar osteoporotic vertebral fractures. BMD was derived from lumbar vertebrae using a conversion equation, and the cross-sectional area (CSA), CSA ratio (CSA psoas muscles divided by CSA erector spinae muscles), and muscle attenuation were measured for the psoas and erector spinae muscles at the levels L2 and L4/5 without dedicated software.
Males showed significantly higher BMD, CSA, and CSA ratios at the levels L2 and L4/5, while females had decreased erector spinae muscle attenuation at L4/5 (p < 0.05). No significant differences between patients with versus without fractures were observed except for BMD (68.5 ± 37.2 mg/ml vs. 91.4 ± 26.8 mg/ml; p < 0.01). Age-adjusted partial correlation testing revealed significant correlations of BMD and the CSA ratio at level L4/5 (r = 0.20; p = 0.03), but not with muscle attenuation (p > 0.05).
Paraspinal muscle characteristics and lumbar BMD can be assessed seamlessly in routine abdominal MDCT without dedicated software. There are level-dependent interactions between paraspinal muscle characteristics as well as lumbar BMD. Vertebral fracture status was independent of paraspinal muscle characteristics.
研究常规腹部多层螺旋 CT（MDCT）中的椎旁肌特征和腰椎骨密度（BMD）及其相关性，以及骨质疏松性椎体骨折对这些相关性的影响。
回顾性纳入 116 例（69.7±8.1 岁，72 名男性）接受常规腹部 MDCT（肿瘤分期和/或肿瘤复发随访）的患者，并根据是否存在腰椎骨质疏松性椎体骨折将其分为骨折组和对照组（年龄和性别匹配）。使用转换方程从腰椎获得 BMD，并在没有专用软件的情况下测量 L2 和 L4/5 水平的竖脊肌和腰大肌的横截面积（CSA）、CSA 比值（CSA 腰大肌/CSA 竖脊肌肌肉）和肌肉衰减。
男性在 L2 和 L4/5 水平的 BMD、CSA 和 CSA 比值明显较高，而女性在 L4/5 水平的竖脊肌衰减降低（p<0.05）。除 BMD 外（68.5±37.2 mg/ml 比 91.4±26.8 mg/ml；p<0.01），两组患者之间无显著差异。年龄调整的偏相关检验显示，L4/5 水平的 BMD 和 CSA 比值存在显著相关性（r=0.20；p=0.03），但与肌肉衰减无相关性（p>0.05）。
无需专用软件即可在常规腹部 MDCT 中无缝评估椎旁肌特征和腰椎 BMD。椎旁肌特征和腰椎 BMD 之间存在与水平相关的相互作用。椎体骨折状态与椎旁肌特征无关。
