Hofer Johannes, Blum Marina, Wiltsche Regina, Deluggi Nikoletta, Holzinger Daniel, Fellinger Johannes, Tulzer Gerald, Blum Gina, Oberhuber Raphael
Research Institute for Developmental Medicine, Johannes Kepler University of Linz, Linz, Austria.
Institute of Neurology of Senses and Language, Hospital of St. John of God, Linz, Austria.
Front Pediatr. 2024 May 23;12:1340495. doi: 10.3389/fped.2024.1340495. eCollection 2024.
Children with congenital heart defects (CHD) are at risk for a range of developmental disabilities that challenge cognition, executive functioning, self-regulation, communication, social-emotional functioning, and motor skills. Ongoing developmental surveillance is therefore key to maximizing neurodevelopmental outcome opportunities. It is crucial that the measures used cover the spectrum of neurodevelopmental domains relevant to capturing possible predictors and malleable factors of child development.
This work aimed to synthesize the literature on neurodevelopmental measures and the corresponding developmental domains assessed in children aged 1-8 years with complex CHD.
PubMed was searched for terms relating to psycho-social, cognitive and linguistic-communicative outcomes in children with CHD. 1,380 papers with a focus on complex CHD that reported neurodevelopmental assessments were identified; ultimately, data from 78 articles that used standardized neurodevelopmental assessment tools were extracted.
Thirty-nine (50%) of these excluded children with syndromes, and 9 (12%) excluded children with disorders of intellectual development. 10% of the studies were longitudinal. The neurodevelopmental domains addressed by the methods used were: 53% cognition, 16% psychosocial functioning, 18% language/communication/speech production, and 13% motor development-associated constructs.
Data on social communication, expressive and receptive language, speech motor, and motor function are underrepresented. There is a lack of research into everyday use of language and into measures assessing language and communication early in life. Overall, longitudinal studies are required that include communication measures and their interrelations with other developmental domains.
患有先天性心脏病（CHD）的儿童面临一系列发育障碍的风险，这些障碍对认知、执行功能、自我调节、沟通、社会情感功能和运动技能构成挑战。因此，持续的发育监测是最大化神经发育结果机会的关键。所使用的测量方法涵盖与捕捉儿童发育的可能预测因素和可塑因素相关的神经发育领域范围至关重要。
这项工作旨在综合有关1 - 8岁患有复杂CHD儿童的神经发育测量方法及相应评估的发育领域的文献。
在PubMed上搜索与CHD儿童心理社会、认知和语言交流结果相关的术语。共识别出1380篇聚焦复杂CHD且报告了神经发育评估的论文；最终，提取了78篇使用标准化神经发育评估工具的文章的数据。
其中39篇（50%）排除了患有综合征的儿童，9篇（12%）排除了智力发育障碍儿童。10%的研究是纵向研究。所使用方法涉及的神经发育领域包括：53%为认知，16%为心理社会功能，18%为语言/沟通/言语产生，13%为与运动发育相关的结构。
关于社会沟通、表达性和接受性语言、言语运动和运动功能的数据代表性不足。缺乏对语言日常使用以及早期评估语言和沟通的测量方法的研究。总体而言，需要进行包括沟通测量及其与其他发育领域相互关系的纵向研究。
