Department of Infection Control and Vaccine, Norwegian Institute of Public Health, Oslo, Norway.
Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.
Hum Vaccin Immunother. 2024 Dec 31;20(1):2361499. doi: 10.1080/21645515.2024.2361499. Epub 2024 Jun 7.
Maternal vaccination against pertussis is safe and provides effective protection against pertussis for the newborn, but the vaccine coverage rate remains generally low. Norway is currently planning for introduction of routine maternal pertussis vaccination. To assess maternal pertussis vaccination acceptance among pregnant Norwegian women, we surveyed women at 20-40 weeks gestation in 2019. Among the 1,148 pregnant women participating in this cross-sectional study, 73.8% reported they would accept pertussis vaccination during pregnancy if it was recommended, 6.9% would not accept and 19.2% were undecided. Predictors for low likelihood of accepting pertussis vaccination during pregnancy included low confidence in health authorities and in maternal pertussis vaccination safety and effectiveness, low awareness and adherence to influenza vaccination during pregnancy, and low awareness of pertussis vaccination. The major reasons reported for not accepting or being undecided about maternal pertussis vaccination were lack of information on vaccine safety for both mother and child. Most women reported that they would consult their general practitioner or a midwife for information if they were offered maternal pertussis vaccination. General practitioners and midwives were also regarded as the most trustworthy sources of information if the women were in doubt about accepting vaccination. We conclude that information addressing safety concerns and raising awareness about maternal pertussis vaccination could increase acceptance of maternal pertussis vaccination. Our findings highlight the pivotal role of the antenatal and primary health care services in providing such information to pregnant women.
母亲接种百日咳疫苗是安全的,并为新生儿提供有效的百日咳保护,但疫苗接种率普遍较低。挪威目前正在计划常规接种母亲百日咳疫苗。为了评估挪威孕妇对母亲百日咳疫苗接种的接受程度,我们在 2019 年对 20-40 孕周的孕妇进行了调查。在这项横断面研究中,有 1148 名孕妇参加,其中 73.8%的孕妇表示如果建议她们在怀孕期间接种百日咳疫苗,她们会接受,6.9%的孕妇不会接受,19.2%的孕妇尚未决定。预测在怀孕期间不太可能接受百日咳疫苗接种的因素包括对卫生当局和母亲百日咳疫苗接种安全性和有效性的信心低、对怀孕期间流感疫苗接种的认识和依从性低、以及对百日咳疫苗接种的认识低。不接受或对母亲百日咳疫苗接种犹豫不决的主要原因是缺乏疫苗对母亲和儿童安全性的信息。大多数妇女报告说,如果提供母亲百日咳疫苗接种,她们将向她们的全科医生或助产士咨询信息。如果妇女对接种疫苗有疑问,全科医生和助产士也被认为是最值得信赖的信息来源。我们的结论是,提供解决安全性问题的信息并提高对母亲百日咳疫苗接种的认识,可以提高母亲百日咳疫苗接种的接受程度。我们的研究结果强调了产前和初级卫生保健服务在向孕妇提供此类信息方面的关键作用。