Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA.
National Center for Child and Adolescent Health, Ministry of Health, Francisco de P. Miranda 177, Lomas de Plateros, Álvaro Obregón, 01600 Mexico City, Mexico.
Vaccine. 2014 Feb 7;32(7):785-92. doi: 10.1016/j.vaccine.2013.12.054. Epub 2014 Jan 4.
Adult booster vaccination against pertussis can help prevent severe infections in young infants. We examined influences on intention to accept pertussis booster vaccination among pregnant women in Mexico City.
We conducted a cross-sectional survey, recruiting convenience samples of pregnant women receiving prenatal care from three public healthcare centers between March and May 2012. Our primary outcome was intention to accept pertussis vaccination during pregnancy. We examined socio-demographic factors, vaccination history, pertussis knowledge, perceptions of vaccine information sources, and other potential influences on vaccine decision-making.
A total of 402 pregnant women agreed to participate, of which 387 (96%) provided their intention to accept or decline pertussis vaccination. Among respondents, 57% intended to accept a pertussis booster vaccine if offered, but only 16% had ever heard of pertussis, and only 2% knew someone who had contracted this disease. Over 80% of respondents would accept pertussis vaccination if recommended by an obstetrician-gynecologist. The most frequently selected reasons to refuse pertussis vaccination were concerns that the vaccine might harm the unborn baby or pregnant woman. In multivariate analysis, rating doctors and nurses as good sources of vaccine information, and having ever heard of pertussis, were independently associated with intention to accept pertussis vaccination.
Promoting patient awareness about pertussis disease and vaccine safety, and encouraging general practitioners, nurses and obstetricians to recommend pertussis booster vaccine, may increase vaccine uptake among pregnant women.
成人百白破加强免疫可帮助预防婴幼儿严重感染。我们研究了墨西哥城孕妇接受百白破加强免疫的意愿的影响因素。
我们进行了一项横断面调查，于 2012 年 3 月至 5 月期间，在 3 家公共医疗中心招募接受产前保健的孕妇进行便利抽样。主要结局是孕妇在怀孕期间接受百白破疫苗接种的意愿。我们研究了社会人口因素、疫苗接种史、百日咳知识、对疫苗信息来源的看法以及对疫苗决策的其他潜在影响。
共有 402 名孕妇同意参加，其中 387 名（96%）提供了接受或拒绝百白破疫苗接种的意愿。在应答者中，57%的人如果提供，他们打算接受百白破加强疫苗，但只有 16%听说过百日咳，只有 2%知道有人患过这种病。超过 80%的应答者会接受如果妇产科医生推荐百白破疫苗接种。拒绝百白破疫苗接种的最常见原因是担心疫苗可能会伤害未出生的婴儿或孕妇。在多变量分析中，将医生和护士评为疫苗信息的良好来源，以及听说过百日咳，与接受百白破疫苗接种的意愿独立相关。
提高患者对百日咳病和疫苗安全性的认识，并鼓励全科医生、护士和妇产科医生推荐百白破加强疫苗，可能会增加孕妇对百白破疫苗的接种率。
