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头皮神经阻滞在改善脑膜瘤切除术后患者康复质量中的作用:一项随机对照临床试验。

Role of scalp nerve block in improving the quality of rehabilitation in patients after meningioma resection: A randomized controlled clinical trial.

机构信息

Department of Anesthesiology, People's Hospital of Qiannan, Qiannan, China.

Department of Neurosurgery, People's Hospital of Qiannan, Qiannan, China.

出版信息

Medicine (Baltimore). 2024 Jun 7;103(23):e38324. doi: 10.1097/MD.0000000000038324.

Abstract

BACKGROUND

In this study, we analyzed whether scalp nerve block with ropivacaine can improve the quality of rehabilitation in patients after meningioma resection.

METHODS

We included 150 patients who were undergoing craniotomy in our hospital and categorized them into 2 groups - observation group (patients received an additional regional scalp nerve block anesthesia) and control group (patients underwent intravenous general anesthesia for surgery), using the random number table method approach (75 patients in each group). The main indicator of the study was the Karnofsky Performance Scale scores of patients at 3 days postoperatively, and the secondary indicator was the anesthesia satisfaction scores of patients after awakening from anesthesia. The application value of different anesthesia modes was studied and compared in the 2 groups.

RESULTS

Patients in the observation group showed better anesthesia effects than those in the control group, with significantly higher Karnofsky Performance Scale scores at 3 days postoperatively (75.02 vs 66.43, P < .05) and anesthesia satisfaction scores. Compared with patients in the control group, patients in the observation group had lower pain degrees at different times after the surgery, markedly lower dose of propofol and remifentanil for anesthesia, and lower incidence of adverse reactions and postoperative complications. In addition, the satisfaction score of the patients and their families for the treatment was higher and the results of all the indicators were better in the observation group than in the control group, with statistically significant differences (P < .05).

CONCLUSION

Scalp nerve block with ropivacaine significantly improves the quality of short-term postoperative rehabilitation in patients undergoing elective craniotomy for meningioma resection. This is presumably related to the improvements in intraoperative hemodynamics, relief from postoperative pain, and reduction in postoperative nausea and vomiting.

摘要

背景

本研究旨在分析罗哌卡因头皮神经阻滞能否改善脑膜瘤切除术后患者的康复质量。

方法

我们纳入了在我院行开颅手术的 150 例患者,并采用随机数字表法将其分为观察组(患者接受额外的区域头皮神经阻滞麻醉)和对照组(患者接受静脉全身麻醉进行手术),每组 75 例。研究的主要指标是术后 3 天患者的 Karnofsky 表现量表评分,次要指标是患者麻醉苏醒后的麻醉满意度评分。研究比较了两组不同麻醉模式的应用价值。

结果

观察组患者的麻醉效果优于对照组,术后 3 天 Karnofsky 表现量表评分明显更高(75.02 分比 66.43 分,P<.05),麻醉满意度评分也更高。与对照组患者相比,观察组患者在手术后不同时间的疼痛程度更低,麻醉所需的异丙酚和瑞芬太尼剂量明显更低,不良反应和术后并发症的发生率也更低。此外,观察组患者及其家属对治疗的满意度更高,各项指标的结果均优于对照组,差异有统计学意义(P<.05)。

结论

罗哌卡因头皮神经阻滞可显著改善择期行脑膜瘤切除术的患者术后短期康复质量。这可能与术中血流动力学的改善、术后疼痛的缓解以及术后恶心和呕吐的减少有关。

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