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健康成年人重复唾液吞咽测试的正常值及影响测试结果的临床因素。

Normative Values of the Repetitive Saliva Swallow Test and Clinical Factors Affecting the Test Scores in Healthy Adults.

机构信息

Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The Goldman Medical School, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

Dysphagia. 2024 Dec;39(6):1193-1201. doi: 10.1007/s00455-024-10702-5. Epub 2024 Jun 7.

Abstract

The Repetitive Saliva Swallow Test (RSST) is a screening test for oropharyngeal dysphagia during which the subject is asked to perform as many empty swallows as possible in 30 s. Previous validation studies found a cutoff value of 3 > swallows as pathological. The aims of this study were to establish the normative values of the RSST and to examine the effect of clinical factors on RSST scores in healthy adults. A cross-sectional study of 280 adults. An equal number of females and males were recruited for each decade of life, ages 20 to 90 years. Patients reporting swallowing difficulties, history of neurologic disorders, or head and neck surgery or radiation were excluded. Data collected included RSST scores, number and type of comorbidities, number of prescribed medications, body mass index, smoking habits, and self-assessment xerostomia questionnaire. The mean RSST score for the entire cohort was 7.01 ± 2.86. Males had a higher RSST score (7.6 ± 3.04 compared to 6.47 ± 2.56, p = 0.001). Age showed an inverse correlation with RSST scores (Pearson's Correlation Coefficient (PCC) = -0.463, p < 0.0001), as well as body mass index, BMI (PCC = -0.2, p < 0.0001), number of co-morbidities (PCC=-0.344, p < 0.0001) and number of prescribed medications (PCC= -0.425, p < 0.0001). Self-reported amount of saliva positively correlated (PCC = 1.05, p = 0.04) with RSST scores. A multivariate logistic regression analysis was performed. Age, sex, BMI, and number of prescribed medications were found as significant independent factors on RSST scores. RSST scores in healthy adults decline with age and are lower in females, individuals taking multiple medications and with higher BMI. Mean RSST for all age groups did not fall beneath the previously established pathological cut-off.

摘要

重复性唾液吞咽测试(RSST)是一种用于筛查口咽吞咽困难的测试方法,要求受试者在 30 秒内尽可能多地进行空吞咽。之前的验证研究发现,3 次以上的吞咽被认为是病理性的。本研究旨在建立 RSST 的正常值,并探讨健康成年人中临床因素对 RSST 评分的影响。这是一项对 280 名成年人进行的横断面研究。每个年龄段(20 至 90 岁)均招募了相等数量的男性和女性。排除有吞咽困难、神经系统疾病、头颈部手术或放疗史的患者。收集的数据包括 RSST 评分、合并症的数量和类型、处方药物的数量、体重指数、吸烟习惯以及口干自我评估问卷。整个队列的平均 RSST 得分为 7.01±2.86。男性的 RSST 评分更高(7.6±3.04 与 6.47±2.56 相比,p=0.001)。年龄与 RSST 评分呈负相关(皮尔逊相关系数(PCC)=-0.463,p<0.0001),体重指数(PCC=-0.2,p<0.0001)、合并症数量(PCC=-0.344,p<0.0001)和处方药物数量(PCC=-0.425,p<0.0001)也呈负相关。自我报告的唾液量与 RSST 评分呈正相关(PCC=1.05,p=0.04)。进行了多变量逻辑回归分析。发现年龄、性别、BMI 和处方药物数量是 RSST 评分的显著独立因素。健康成年人的 RSST 评分随年龄下降,女性、服用多种药物和 BMI 较高的人评分较低。所有年龄组的平均 RSST 均未低于之前建立的病理性截断值。

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