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显微镜下血尿的存在并不能预测儿童有临床意义的腹腔内损伤。

Presence of Microscopic Hematuria Does Not Predict Clinically Important Intra-Abdominal Injury in Children.

机构信息

From the Department of Pediatric General, Thoracic and Minimally Invasive Surgery, St Christopher's Hospital for Children.

Drexel University College of Medicine, Philadelphia.

出版信息

Pediatr Emerg Care. 2024 Aug 1;40(8):e139-e142. doi: 10.1097/PEC.0000000000003210. Epub 2024 Jun 7.

Abstract

OBJECTIVE

Screening for blunt intra-abdominal injury in children often includes directed laboratory evaluation that guides need for computed tomography. We sought to evaluate the use of urinalysis in identifying patients with clinically important intraabdominal injury ( ci -IAI).

METHODS

A retrospective chart review was performed for all patients less than 18 years who presented with blunt mechanisms at a level I trauma center between 2016 and 2019. Exclusion criteria included transfer from an outside facility, physical abuse, and death within thirty minutes of arrival. Demographics, physical exam findings, serum chemistries, urinalysis, and imaging were reviewed. Clinically important intraabdominal injury was defined as injury requiring ≥2 nights admission, blood transfusion, angiography with embolization, or therapeutic surgery.

RESULTS

Two hundred forty patients were identified. One hundred sixty-five had a completed urinalysis. For all patients an abnormal chemistry panel and abnormal physical exam had a sensitivity of 88.9% and a negative predictive value of 99.3%. Nine patients had a ci -IAI. Patients with a ci -IAI were more likely to have abdominal pain, tenderness on exam, and elevated hepatic enzymes. When patients were stratified by the presence of an abnormal chemistry or physical exam with or without microscopic hematuria, urinalysis did not improve the ability to identify patients with a ci -IAI. In fact, presence of microscopic hematuria increased the rate of false positives by 12%.

CONCLUSIONS

Microscopic hematuria was not a useful marker for ci -IAI and may lead to falsely assuming a more serious injury.

摘要

目的

在儿童钝性腹部损伤的筛查中,通常包括有针对性的实验室评估,以指导是否需要进行计算机断层扫描。我们旨在评估尿分析在识别具有临床重要性的腹腔内损伤(ci-IAI)患者中的作用。

方法

对 2016 年至 2019 年期间在一级创伤中心因钝性机制就诊的所有年龄小于 18 岁的患者进行回顾性病历审查。排除标准包括从外部医疗机构转来、身体虐待和到达后 30 分钟内死亡。回顾了人口统计学、体格检查结果、血清化学、尿液分析和影像学检查。将临床重要的腹腔内损伤定义为需要≥2 晚住院、输血、血管造影栓塞或治疗性手术的损伤。

结果

共确定了 240 例患者。其中 165 例完成了尿液分析。对于所有患者,异常化学指标和异常体格检查的敏感性为 88.9%,阴性预测值为 99.3%。9 例患者发生 ci-IAI。发生 ci-IAI 的患者更可能出现腹痛、腹部触痛和肝酶升高。当患者根据存在异常化学或体格检查与或不伴镜下血尿进行分层时,尿液分析并不能提高识别具有 ci-IAI 的患者的能力。事实上,镜下血尿使假阳性率增加了 12%。

结论

镜下血尿不是 ci-IAI 的有用标志物,可能导致错误地假设更严重的损伤。

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