Division of Dermatology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA.
Arch Dermatol Res. 2024 Jun 8;316(7):351. doi: 10.1007/s00403-024-02973-7.
Fast gut cutaneous sutures have become more prominent due to their low tissue reactivity, rapid absorption, and elimination of suture removal visits. It is not known how fast gut sutures compare to other closure modalities.
A comprehensive literature review was conducted to identify randomized controlled trials comparing fast gut sutures to alternative closure methods during dermatologic surgery. Data collected included patient and physician assessed cosmetic outcome as well as standardized complication rates.
Six studies were included in final analysis and reported on 208 patients. Fast gut sutures were associated with lower physician opinions of final scar when compared to polypropylene sutures (SMD 0.438; 95% CI 0.082 to 0.794). No differences existed between physician opinion of fast gut sutures and cyanoacrylate tissue adhesive (SMD - 0.024; 95% CI - 0.605 to 0.556). Complications with fast gut suture placement were rare, and included infection, dehiscence, and hematomas. Fast gut sutures were less likely to experience wound dehiscence than tissue adhesive (p = 0.01).
If no contraindications to polypropylene sutures exist, they may provide superior cosmetic outcomes compared to fast gut sutures. Further research is required to better quantify cosmetic outcomes and optimal use of fast gut sutures.
由于快速肠线的组织反应低、吸收迅速且无需拆线,因此在医学美容领域得到了广泛应用。目前还不清楚快速肠线与其他缝合方式相比有何优势。
我们进行了全面的文献回顾,以确定在皮肤科手术中比较快速肠线与其他闭合方法的随机对照试验。收集的数据包括患者和医生评估的美容效果以及标准化的并发症发生率。
最终有 6 项研究纳入分析,共纳入 208 例患者。与聚丙烯缝线相比,快速肠线的医生对最终瘢痕的评价较低(SMD 0.438;95%CI 0.082 至 0.794)。与氰基丙烯酸酯组织粘合剂相比,医生对快速肠线的评价没有差异(SMD -0.024;95%CI -0.605 至 0.556)。快速肠线的并发症罕见,包括感染、裂开和血肿。与组织粘合剂相比,快速肠线发生伤口裂开的可能性较小(p=0.01)。
如果不存在聚丙烯缝线的禁忌证,其美容效果可能优于快速肠线。需要进一步研究来更好地量化美容效果并优化快速肠线的使用。