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辅助高压氧治疗难治性坏疽性脓皮病病例。

Adjunctive hyperbaric oxygen treatment for challenging pyoderma gangrenosum cases.

机构信息

Department of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.

出版信息

J Tissue Viability. 2024 Aug;33(3):449-451. doi: 10.1016/j.jtv.2024.06.001. Epub 2024 Jun 5.

Abstract

INTRODUCTION

Pyoderma gangrenosum (PG) is a rare, difficult-to-treat neutrophilic ulcerative cutaneous condition that severely impacts those affected. Treatment options for PG are limited, and disease remission is not guaranteed. Hyperbaric oxygen treatment is a potential therapeutic option for treating various ulcerative conditions not frequently utilized for PG.

CASE REPORT

We present a case of a patient with treatment-resistant PG who achieved remission with adjunctive HBOT, and then later had difficulty achieving remission without HBOT during a future flare.

DISCUSSION

HBOT should be more readily considered as a treatment option for those with PG.

摘要

简介

坏疽性脓皮病(PG)是一种罕见的、难以治疗的中性粒细胞溃疡性皮肤疾病,严重影响患者的生活。PG 的治疗选择有限,疾病缓解并不能保证。高压氧治疗是治疗各种溃疡性疾病的一种潜在治疗选择,但并不常用于 PG。

病例报告

我们报告了一例治疗抵抗性 PG 患者,辅助高压氧治疗后获得缓解,随后在未来的一次发作中,没有高压氧治疗则难以缓解。

讨论

高压氧治疗应更被视为 PG 患者的一种治疗选择。

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