Department of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.
J Tissue Viability. 2024 Aug;33(3):449-451. doi: 10.1016/j.jtv.2024.06.001. Epub 2024 Jun 5.
Pyoderma gangrenosum (PG) is a rare, difficult-to-treat neutrophilic ulcerative cutaneous condition that severely impacts those affected. Treatment options for PG are limited, and disease remission is not guaranteed. Hyperbaric oxygen treatment is a potential therapeutic option for treating various ulcerative conditions not frequently utilized for PG.
We present a case of a patient with treatment-resistant PG who achieved remission with adjunctive HBOT, and then later had difficulty achieving remission without HBOT during a future flare.
HBOT should be more readily considered as a treatment option for those with PG.
坏疽性脓皮病(PG)是一种罕见的、难以治疗的中性粒细胞溃疡性皮肤疾病,严重影响患者的生活。PG 的治疗选择有限,疾病缓解并不能保证。高压氧治疗是治疗各种溃疡性疾病的一种潜在治疗选择,但并不常用于 PG。
我们报告了一例治疗抵抗性 PG 患者,辅助高压氧治疗后获得缓解,随后在未来的一次发作中,没有高压氧治疗则难以缓解。
高压氧治疗应更被视为 PG 患者的一种治疗选择。