坏疽性脓皮病对手术干预和高压氧治疗的良好反应。
A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma gangrenosum.
作者信息
Altunay Ilknur, Kucukunal Asli, Sarikaya Sezgi, Tukenmez Demirci Gulsen
机构信息
Department of Dermatology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.
出版信息
Int Wound J. 2014 Aug;11(4):350-3. doi: 10.1111/j.1742-481X.2012.01102.x. Epub 2012 Oct 29.
Abstract
Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterised with ulcerations. Inflammatory bowel diseases (ulcerative colitis and Crohn's disease) and haematologic diseases (leukaemia, preleukaemia and monoclonal gammopathy) have been reported in about 40-50% of PG patients in whom the treatment of the underlying disease is important for the improvement of the lesions. We herein report a colorectal adenocarcinoma patient with PG, who responded partially to topical treatments and systemic immunosuppressants and healed completely with the aid of surgical wound repair and hyperbaric oxygen therapy.
摘要
坏疽性脓皮病（PG）是一种以溃疡为特征的嗜中性皮病。约40%-50%的PG患者伴有炎症性肠病（溃疡性结肠炎和克罗恩病）和血液系统疾病（白血病、白血病前期和单克隆丙种球蛋白病），对这些基础疾病的治疗对于改善皮损很重要。我们在此报告1例患有PG的结肠直肠癌患者，该患者对局部治疗和全身免疫抑制剂部分有效，并在手术伤口修复和高压氧治疗的帮助下完全愈合。
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