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使用Spectrum艾滋病影响模块对孕妇中艾滋病毒流行率数据和预防母婴传播覆盖率进行三角测量和估计的指南。

Guidance for triangulating data and estimates of HIV prevalence among pregnant women and coverage of PMTCT using the Spectrum AIDS Impact Module.

作者信息

Walters Magdalene K, Korenromp Eline L, Yakusik Anna, Wanyeki Ian, Kaboré André, Poimouribou Arthur, Ki Célestine, Dao Coumbo, Bambara Paul, Derme Salam, Ouedraogo Théophile, Tang Kai Hon, Boily Marie-Claude, Mahy Mary, Imai-Eaton Jeffrey W

出版信息

medRxiv. 2024 May 31:2024.05.29.24306862. doi: 10.1101/2024.05.29.24306862.

Abstract

BACKGROUND

Most countries use the Spectrum AIDS Impact Module (Spectrum-AIM), antenatal care routine HIV testing, and antiretroviral treatment data to estimate HIV prevalence among pregnant women. Non-representative programme data may lead to inaccurate estimates HIV prevalence and treatment coverage for pregnant women.

SETTING

154 locations in 126 countries.

METHODS

Using 2023 UNAIDS HIV estimates, we calculated three ratios: (1) HIV prevalence among pregnant women to all women 15-49y (prevalence), (2) ART coverage before pregnancy to women 15-49y ART coverage (ART pre-pregnancy), and (3) ART coverage at delivery to women 15-49y ART coverage (PMTCT coverage). We developed an algorithm to identify and adjust inconsistent results within regional ranges in Spectrum-AIM, illustrated using Burkina Faso's estimates.

RESULTS

In 2022, the mean regional ratio of prevalence among pregnant women to all women ranged from 0.68 to 0.95. ART coverage pre-pregnancy ranged by region from 0.40 to 1.22 times ART coverage among all women. Mean regional PMTCT coverage ratios ranged from 0.85 to 1.51. The prevalence ratio in Burkina Faso was 1.59, above the typical range 0.62-1.04 in western and central Africa. Antenatal clinics reported more PMTCT recipients than estimated HIV-positive pregnant women from 2015 to 2019. We adjusted inputted PMTCT programme data to enable consistency of HIV prevalence among pregnant women from programmatic routine HIV testing at antenatal clinics with values typical for Western and central Africa.

CONCLUSION

These ratios offer Spectrum-AIM users a tool to gauge the consistency of their HIV prevalence and treatment coverage estimates among pregnant women with other countries in the region.

摘要

背景

大多数国家使用艾滋病影响评估模块(Spectrum-AIM)、产前保健常规HIV检测以及抗逆转录病毒治疗数据来估计孕妇中的HIV流行率。非代表性的项目数据可能导致对孕妇HIV流行率和治疗覆盖率的估计不准确。

地点

126个国家的154个地点。

方法

利用2023年联合国艾滋病规划署的HIV估计数,我们计算了三个比率:(1)孕妇中的HIV流行率与所有15至49岁女性的HIV流行率之比(流行率),(2)孕前抗逆转录病毒治疗覆盖率与15至49岁女性抗逆转录病毒治疗覆盖率之比(孕前抗逆转录病毒治疗),以及(3)分娩时抗逆转录病毒治疗覆盖率与15至49岁女性抗逆转录病毒治疗覆盖率之比(预防母婴传播覆盖率)。我们开发了一种算法,以识别和调整Spectrum-AIM区域范围内不一致的结果,并以布基纳法索的估计数为例进行说明。

结果

2022年,孕妇中HIV流行率与所有女性HIV流行率的平均区域比率在0.68至0.95之间。孕前抗逆转录病毒治疗覆盖率因地区而异,是所有女性抗逆转录病毒治疗覆盖率的0.40至1.22倍。预防母婴传播覆盖率的平均区域比率在0.85至1.51之间。布基纳法索的流行率比率为1.59,高于西非和中非的典型范围0.62至1.04。2015年至2019年,产前诊所报告的预防母婴传播接受者多于估计的HIV阳性孕妇。我们调整了输入的预防母婴传播项目数据,以使产前诊所常规HIV检测得出的孕妇HIV流行率与西非和中非的典型值保持一致。

结论

这些比率为Spectrum-AIM用户提供了一种工具,用以衡量他们对孕妇HIV流行率和治疗覆盖率的估计与该地区其他国家的估计之间的一致性。

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