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肝硬化相关性急性肾损伤的床旁超声检查:我的操作方法。

Point-of-care ultrasonography in cirrhosis-related acute kidney injury: How I do it.

作者信息

Koratala Abhilash

机构信息

Division of Nephrology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, United States.

出版信息

World J Crit Care Med. 2024 Jun 9;13(2):93812. doi: 10.5492/wjccm.v13.i2.93812.

DOI:10.5492/wjccm.v13.i2.93812
PMID:38855271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11155506/
Abstract

Discerning the etiology of acute kidney injury (AKI) in cirrhotic patients remains a formidable challenge due to diverse and overlapping causes. The conventional approach of empiric albumin administration for suspected volume depletion may inadvertently lead to fluid overload. In the recent past, point-of-care ultrasonography (POCUS) has emerged as a valuable adjunct to clinical assessment, offering advantages in terms of diagnostic accuracy, rapidity, cost-effectiveness, and patient satisfaction. This review provides insights into the strategic use of POCUS in evaluating cirrhotic patients with AKI. The review distinguishes basic and advanced POCUS, emphasizing a 5-point basic POCUS protocol for efficient assessment. This protocol includes evaluations of the kidneys and urinary bladder for obstructive nephropathy, lung ultrasound for detecting extravascular lung water, inferior vena cava (IVC) ultrasound for estimating right atrial pressure, internal jugular vein ultrasound as an alternative to IVC assessment, and focused cardiac ultrasound for assessing left ventricular (LV) systolic function and identifying potential causes of a plethoric IVC. Advanced POCUS delves into additional Doppler parameters, including stroke volume and cardiac output, LV filling pressures and venous congestion assessment to diagnose or prevent iatrogenic fluid overload. POCUS, when employed judiciously, enhances the diagnostic precision in evaluating AKI in cirrhotic patients, guiding appropriate therapeutic interventions, and minimizing the risk of fluid-related complications.

摘要

由于病因多样且相互重叠,明确肝硬化患者急性肾损伤(AKI)的病因仍然是一项艰巨的挑战。对于疑似容量不足的患者,经验性给予白蛋白的传统方法可能会无意中导致液体超负荷。近年来,床旁超声检查(POCUS)已成为临床评估的一项有价值的辅助手段,在诊断准确性、快速性、成本效益和患者满意度方面具有优势。本综述深入探讨了POCUS在评估肝硬化合并AKI患者中的策略性应用。该综述区分了基础POCUS和高级POCUS,强调了一个用于高效评估的5点基础POCUS方案。该方案包括对肾脏和膀胱进行评估以排查梗阻性肾病,进行肺部超声检查以检测血管外肺水,进行下腔静脉(IVC)超声检查以估计右心房压力,进行颈内静脉超声检查作为IVC评估的替代方法,以及进行心脏重点超声检查以评估左心室(LV)收缩功能并确定IVC扩张的潜在原因。高级POCUS则深入研究额外的多普勒参数,包括每搏输出量和心输出量、LV充盈压以及静脉淤血评估,以诊断或预防医源性液体超负荷。POCUS若合理使用,可提高评估肝硬化患者AKI的诊断精度,指导适当的治疗干预,并将与液体相关并发症的风险降至最低。

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