类风湿关节炎患者感染新冠病毒后关节症状复发情况的调查：横断面研究
Investigation of recurrence of joint symptoms after COVID-19 in patients with rheumatoid arthritis: Cross-sectional study.
作者信息
Akbarpour Afsaneh, Salesi Mansour, Babak Anahita
机构信息
Department of Internal Medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Internal Medicine, Division of Rheumatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Res Med Sci. 2024 Apr 29;29:21. doi: 10.4103/jrms.jrms_782_22. eCollection 2024.
BACKGROUND
In this study, the relationship between involvement by COVID-19 and the recurrence of symptoms of rheumatoid arthritis (RA) was investigated.
MATERIALS AND METHODS
This cross-sectional study was conducted on 112 patients with RA with and without a history of COVID-19. The severity and recurrence of RA symptoms were measured and recorded by the Disease Activity Score in 28 joints (DAS-28) index and clinical evaluations by a rheumatologist.
RESULTS
The results showed that the recurrence of RA in patients with and without a history of COVID-19 had a statistically significant difference ( < 0.001). In addition, there was a statistically significant relationship between erythrocyte sedimentation rate, visual analogue scale (VAS), tender joint count, swollen joint count, and DAS-28 and the history of COVID-19 ( < 0.05).
CONCLUSION
The present study showed that infection with COVID-19 leads to the recurrence of joint symptoms in RA patients.
背景
在本研究中，调查了新型冠状病毒肺炎（COVID-19）感染与类风湿关节炎（RA）症状复发之间的关系。
材料与方法
本横断面研究针对112例有或无COVID-19病史的类风湿关节炎患者进行。通过28个关节疾病活动评分（DAS-28）指数测量并记录类风湿关节炎症状的严重程度和复发情况，并由风湿病学家进行临床评估。
结果
结果显示，有和无COVID-19病史的患者类风湿关节炎复发情况存在统计学显著差异（<0.001）。此外，红细胞沉降率、视觉模拟评分（VAS）、压痛关节数、肿胀关节数和DAS-28与COVID-19病史之间存在统计学显著关系（<0.05）。
结论
本研究表明，COVID-19感染会导致类风湿关节炎患者关节症状复发。
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