Thomas Mathew, Al Kashroom Hatem, Reddy Shilpa, Zaccarini Daniel, Willer Katherine
Department of Internal Medicine, State University of New York (SUNY) Upstate, Syracuse, NY, USA.
Department of Radiology, State University of New York (SUNY) Upstate, Syracuse, NY, USA.
J Clin Med Res. 2024 May;16(5):197-207. doi: 10.14740/jocmr5169. Epub 2024 May 29.
Male breast cancer accounts for less than 1% of all breast cancer cases. The important risk factors for the development of male breast cancer are family history, genetic mutations, obesity, liver disease, alcoholism, exogenous estrogen administration, and radiation exposure to the chest area. Despite its rarity, numerous studies have investigated the data on imaging considerations (mammogram, ultrasound, and magnetic resonance imaging (MRI)), but have addressed only certain aspects of male breast cancer. A comprehensive approach on the imaging characteristics, timing of imaging, prognostication based on imaging characteristics, and follow-up strategies in male breast cancer are still lacking. The purpose of this review article was to provide a comprehensive overview of the imaging findings, optimal timing to obtain imaging, and the appropriate follow-up strategies in male breast cancer survivors. This article also describes how imaging modalities can aid in determining prognosis. By addressing this knowledge gap, the article provides valuable insights for clinicians managing this uncommon yet clinically significant disease.
男性乳腺癌占所有乳腺癌病例的比例不到1%。男性乳腺癌发生的重要风险因素包括家族史、基因突变、肥胖、肝脏疾病、酗酒、外源性雌激素给药以及胸部区域的辐射暴露。尽管男性乳腺癌较为罕见,但众多研究已对成像相关数据(乳房X线摄影、超声和磁共振成像(MRI))进行了调查,但仅涉及男性乳腺癌的某些方面。目前仍缺乏针对男性乳腺癌成像特征、成像时机、基于成像特征的预后评估以及随访策略的综合方法。这篇综述文章的目的是全面概述男性乳腺癌幸存者的成像结果、获取成像的最佳时机以及适当的随访策略。本文还描述了成像方式如何有助于判断预后。通过填补这一知识空白,本文为管理这种罕见但具有临床意义的疾病的临床医生提供了有价值的见解。