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银屑病关节炎:皮肤科医生综合综述 第一部分:流行病学、合并症、发病机制及诊断

Psoriatic arthritis: A comprehensive review for the dermatologist part I: Epidemiology, comorbidities, pathogenesis, and diagnosis.

作者信息

Perez-Chada Lourdes M, Elman Scott, Villa-Ruiz Camila, Armstrong April W, Gottlieb Alice B, Merola Joseph F

机构信息

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, Florida.

出版信息

J Am Acad Dermatol. 2025 May;92(5):969-982. doi: 10.1016/j.jaad.2024.03.058. Epub 2024 Jun 8.

Abstract

Psoriatic arthritis (PsA) is an inflammatory seronegative arthritis strongly associated with psoriasis. Recognition of the clinical features of PsA is critical, as delayed detection and untreated disease may result in irreparable joint damage, impaired physical function, and a significantly reduced quality of life. Dermatologists are poised for the early detection of PsA, as psoriasis predates its development in as many as 80% of patients. In an effort to further acquaint dermatologists with PsA, this review provides a detailed overview, emphasizing its epidemiology, comorbidities, etiopathogenesis, and diagnostic features.

摘要

银屑病关节炎(PsA)是一种与银屑病密切相关的炎症性血清阴性关节炎。认识PsA的临床特征至关重要,因为检测延迟和疾病未治疗可能导致不可修复的关节损伤、身体功能受损以及生活质量显著下降。皮肤科医生具备早期发现PsA的条件,因为在多达80%的患者中,银屑病先于PsA出现。为了让皮肤科医生进一步了解PsA,本综述提供了详细概述,重点介绍其流行病学、合并症、病因发病机制和诊断特征。

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