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体外无创临时心脏起搏:临床试验

External noninvasive temporary cardiac pacing: clinical trials.

作者信息

Zoll P M, Zoll R H, Falk R H, Clinton J E, Eitel D R, Antman E M

出版信息

Circulation. 1985 May;71(5):937-44. doi: 10.1161/01.cir.71.5.937.

Abstract

An external cardiac pacemaker-monitor has been developed that provides safe, effective noninvasive ventricular stimulation that is well tolerated in conscious patients and allows clear recognition of electrocardiographic response. The noninvasive temporary pacemaker (NTP) has now been applied in 134 patients in five hospitals. Stimulation was tolerated well in 73 of 82 conscious patients, and nine found it intolerable. The NTP was effective in evoking electrocardiographic responses in 105 patients; the 29 failures were in the presence of prolonged hypoxia or severe discomfort. The NTP was clinically useful in 82 patients: 43 of 86 were resuscitated from emergency or expected arrest, 38 of 40 were maintained in standby readiness for up to 1 month but did not require stimulation, and one of eight patients with tachycardia obtained some clinical benefit. The NTP was especially useful in 25 patients with complications or contraindications to endocardial pacing and in 57 patients in whom insertion of an endocardial electrode was avoided.

摘要

已研发出一种体外心脏起搏器监测仪,它能提供安全、有效的无创心室刺激,清醒患者对其耐受性良好,并能清晰识别心电图反应。这种无创临时起搏器(NTP)现已在五家医院的134例患者中应用。82例清醒患者中有73例对刺激耐受性良好,9例感觉无法耐受。NTP在105例患者中能有效诱发心电图反应;29例未成功是由于存在长时间缺氧或严重不适。NTP在82例患者中具有临床实用性:86例中有43例从紧急或预期的心搏骤停中复苏,40例中有38例在长达1个月的时间里保持备用状态但无需刺激,8例心动过速患者中有1例获得了一定的临床益处。NTP在25例有并发症或心内膜起搏禁忌症的患者以及57例避免插入心内膜电极的患者中特别有用。

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