Seklaoui Nacera, Izri Arezki, Tablit Islam, Chergou Mustapha, Hamrioui Boussad, Akhoundi Mohammad
Parasitology-Mycology Department, Hospital-University of Nedir Mohammed, Tizi-Ouzou, Algeria.
Parasitology-Mycology Department, Avicenne Hospital, Sorbonne Paris Nord University, Bobigny, France.
Am J Trop Med Hyg. 2024 Jun 11;111(2):377-379. doi: 10.4269/ajtmh.23-0634. Print 2024 Aug 7.
We present the first case of mucocutaneous leishmaniasis in Algeria, diagnosed in an immunocompetent 42-year-old man exhibiting an infiltrated and ulcerated plaque leading to macrocheilitis of the entire lower lip. He was a police officer who lived in a village in Ain El Hammam (Kabylie region, known as an active focus of zoonotic visceral leishmaniasis) without any history of travel for the previous 3 years. He suffered from cutaneous lesions for 22 months due to the misdiagnosis of a skin lesion resembling other diseases such as Crohn disease or sarcoidosis. A compilation of clinical, histopathological, parasitological, and molecular examinations revealed Leishmania infantum as the etiologic agent. The patient was treated with meglumine antimoniate, which resulted in the complete disappearance of the lesion 4 months after treatment.
我们报告了阿尔及利亚首例皮肤黏膜利什曼病病例,该病例发生在一名42岁免疫功能正常的男性身上,其表现为浸润性溃疡性斑块,导致整个下唇出现巨唇炎。他是一名警察,居住在艾因·哈马姆的一个村庄(卡比利亚地区,为人畜共患内脏利什曼病的活跃疫源地),过去3年无任何旅行史。由于皮肤病变被误诊为克罗恩病或结节病等其他疾病,他的皮肤病变持续了22个月。临床、组织病理学、寄生虫学和分子检查结果显示,致病原为婴儿利什曼原虫。患者接受了葡甲胺锑酸盐治疗,治疗4个月后病变完全消失。