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慢性重度主动脉瓣反流患者经右前小切口行主动脉瓣置换术:一项回顾性单中心研究

Aortic valve replacement through right anterior mini-thoracotomy in patients with chronic severe aortic regurgitation: a retrospective single-center study.

作者信息

Jung Eun Yeung, Im Ji Eun, Min Ho-Ki, Lee Seok Soo

机构信息

Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine, Daegu, Korea.

出版信息

J Yeungnam Med Sci. 2024 Jul;41(3):213-219. doi: 10.12701/jyms.2024.00290. Epub 2024 Jun 12.

Abstract

BACKGROUND

Aortic valve replacement (AVR) has recently been performed at many centers using a minimally invasive approach to reduce postoperative mortality, morbidity, and pain. Most previous reports on minimally invasive AVR (MiAVR) have mainly focused on aortic stenosis, and those exclusively dealing with aortic regurgitation (AR) are few. The purpose of this study was to investigate early surgical results and review our experience with patients with chronic severe AR who underwent AVR via right anterior mini-thoracotomy (RAT).

METHODS

Data were retrospectively collected in this single-center study. Eight patients who underwent RAT AVR between January 2020 and January 2024 were enrolled. Short-term outcomes, including the length of hospital stay, in-hospital mortality, postoperative complications, and echocardiographic data, were analyzed.

RESULTS

No in-hospital mortalities were observed. Postoperative atrial fibrillation occurred temporarily in three patients (37.5%). However, none required permanent pacemaker implantation or renal replacement therapy. The median values of ventilator time, length of intensive care unit stay, and hospital stay were 17 hours, 34.5 hours, and 9 days, respectively. Preoperative and postoperative measurements of left ventricular ejection fraction were similar. However, the left ventricular end systolic and diastolic diameters significantly decreased postoperatively from 42 mm to 35.5 mm (p=0.018) and 63 mm to 51 mm (p=0.012), respectively.

CONCLUSION

MiAVR via RAT is a safe and reproducible procedure with acceptable morbidity and complication rates in patients with chronic severe AR. Despite some limitations such as a narrow surgical field and demanding learning curve, MiAVR is a competent method for AR.

摘要

背景

近期,许多中心已采用微创方法进行主动脉瓣置换术(AVR),以降低术后死亡率、发病率和疼痛程度。此前关于微创主动脉瓣置换术(MiAVR)的大多数报告主要集中在主动脉狭窄方面,而专门针对主动脉反流(AR)的报告较少。本研究的目的是调查早期手术结果,并回顾我们对通过右前微创开胸术(RAT)进行AVR的慢性重度AR患者的治疗经验。

方法

在这项单中心研究中进行回顾性数据收集。纳入了2020年1月至2024年1月期间接受RAT AVR的8例患者。分析了短期结果,包括住院时间、院内死亡率、术后并发症和超声心动图数据。

结果

未观察到院内死亡病例。3例患者(37.5%)术后出现短暂性房颤。然而,无一例需要植入永久性起搏器或进行肾脏替代治疗。呼吸机使用时间、重症监护病房住院时间和住院时间的中位数分别为17小时、34.5小时和9天。术前和术后左心室射血分数的测量值相似。然而,术后左心室收缩末期和舒张末期直径分别从42mm显著减小至35.5mm(p = 0.018)和从63mm显著减小至51mm(p = 0.012)。

结论

对于慢性重度AR患者,经RAT的MiAVR是一种安全且可重复的手术,发病率和并发症发生率可接受。尽管存在手术视野狭窄和学习曲线要求高等一些局限性,但MiAVR是治疗AR的一种有效方法。

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