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J Heart Valve Dis. 2018 Jan;27(1):24-31.
2
Effect of SAPIEN 3 Transcatheter Valve Implantation on Health Status in Patients With Severe Aortic Stenosis at Intermediate Surgical Risk: Results From the PARTNER S3i Trial.经导管主动脉瓣置换术对中危外科手术风险严重主动脉瓣狭窄患者健康状况的影响:PARTNER S3i 试验结果。
JACC Cardiovasc Interv. 2018 Jun 25;11(12):1188-1198. doi: 10.1016/j.jcin.2018.02.032. Epub 2018 May 30.
3
Outcomes of minimally invasive aortic valve replacement surgery.微创主动脉瓣置换手术的结果。
Eur J Cardiothorac Surg. 2018 May 1;53(suppl_2):ii19-ii23. doi: 10.1093/ejcts/ezy186.
4
Early Outcomes With the Evolut PRO Repositionable Self-Expanding Transcatheter Aortic Valve With Pericardial Wrap.带心包包裹的 Evolut PRO 可重定位自膨式经导管主动脉瓣的早期结果。
JACC Cardiovasc Interv. 2018 Jan 22;11(2):160-168. doi: 10.1016/j.jcin.2017.10.014.
5
Volume-outcome relationships for transcatheter aortic valve replacement-risk-adjusted and volume stratified analysis of TAVR outcomes.经导管主动脉瓣置换术的容量-结局关系——TAVR结局的风险调整和容量分层分析
Indian Heart J. 2017 Nov-Dec;69(6):700-706. doi: 10.1016/j.ihj.2017.04.017. Epub 2017 May 9.
6
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Ann Cardiothorac Surg. 2017 Sep;6(5):498-503. doi: 10.21037/acs.2017.09.02.
7
Longitudinal Hemodynamics of Transcatheter and Surgical Aortic Valves in the PARTNER Trial.经导管主动脉瓣与外科主动脉瓣在 PARTNER 试验中的纵向血流动力学比较。
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Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).评估经导管和外科主动脉生物瓣膜长期耐久性时结构恶化和瓣膜功能衰竭的标准化定义:欧洲经皮心血管介入协会(EAPCI)的共识声明,得到欧洲心脏病学会(ESC)和欧洲心胸外科学会(EACTS)认可
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J Heart Valve Dis. 2017 Mar;26(2):146-154.
10
Clinical trends in surgical, minimally invasive and transcatheter aortic valve replacement†.外科手术、微创及经导管主动脉瓣置换术的临床趋势†
Eur J Cardiothorac Surg. 2017 Jun 1;51(6):1086-1092. doi: 10.1093/ejcts/ezx008.

退伍军人事务部心脏团队在经导管主动脉瓣置换术和微创外科主动脉瓣置换术方面的经验。

Veterans Affairs Heart Team Experience With Transcatheter Aortic Valve Replacement and Minimally Invasive Surgical Aortic Valve Replacement.

作者信息

Liang Norah E, Wisneski Andrew D, Wang Sue X, Shunk Kendrick A, Wozniak Curtis J, Yang Joseph, Zimmet Jeffrey M, Ge Liang, Tseng Elaine E

机构信息

San Francisco VA Medical Center, 4150 Clement St., 112D, San Francisco, CA 94121 USA.

出版信息

J Invasive Cardiol. 2019 Aug;31(8):217-222. Epub 2019 May 15.

PMID:31088993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8505266/
Abstract

OBJECTIVES

Aortic valve disease is prevalent in the veteran population. Transcatheter aortic valve replacement (TAVR) and minimally invasive surgical aortic valve replacement (MIAVR) are minimally invasive approaches predominantly performed at higher-volume cardiac centers. The study aim was to evaluate our experience with minimally invasive techniques at a Veterans Affairs Medical Center (VAMC), since outcomes from lower-volume federal facilities are relatively unknown.

METHODS

This study examined retrospective data from 228 consecutive patients who underwent treatment for isolated aortic valve disease with MIAVR or TAVR via intent-to-treat at a VAMC between January 2011 and July 2017. Perioperative outcomes were analyzed using Stata version 15.

RESULTS

Operative mortality was 1.1% for MIAVR and 0.7% for TAVR (Χ² P=.79). Median length of hospital stay was 10 days (interquartile range [IQR], 7-14 days) for MIAVR and 4 days for TAVR (IQR, 3-6 days; Mann-Whitney P<.001). Postoperative new-onset atrial fibrillation occurred in 52% of MIAVR patients and 5.2% of TAVR patients (Χ² P<.001). Stroke occurred in 2.2% of MIAVR patients and 3.0% of TAVR patients (Χ² P=.71). In patients who underwent MIAVR, 5.4% required placement of a permanent pacemaker postoperatively, compared with 14% of TAVR patients (Χ² P=.04). Mild paravalvular leak (PVL) affected 2.2% of MIAVR and 28% of TAVR patients, with moderate PVL reported in 2.2% of MIAVR and 3% of TAVR patients (Χ² P<.001).

CONCLUSIONS

The VAMC heart team offers MIAVR and TAVR to veterans with isolated aortic valve disease, and has achieved excellent outcomes despite relatively lower case volumes. Both offer excellent hemodynamic results, with low mortality in a complex population.

摘要

目的

主动脉瓣疾病在退伍军人中很常见。经导管主动脉瓣置换术(TAVR)和微创外科主动脉瓣置换术(MIAVR)是主要在高容量心脏中心进行的微创方法。本研究的目的是评估我们在退伍军人事务医疗中心(VAMC)采用微创技术的经验,因为来自低容量联邦机构的结果相对未知。

方法

本研究检查了2011年1月至2017年7月期间在VAMC接受意向性治疗的228例连续接受孤立性主动脉瓣疾病MIAVR或TAVR治疗的患者的回顾性数据。使用Stata 15版分析围手术期结果。

结果

MIAVR的手术死亡率为1.1%,TAVR为0.7%(Χ² P = 0.79)。MIAVR的中位住院时间为10天(四分位间距[IQR],7 - 14天),TAVR为4天(IQR,3 - 6天;Mann-Whitney P < 0.001)。52%的MIAVR患者和5.2%的TAVR患者术后发生新发房颤(Χ² P < 0.001)。2.2%的MIAVR患者和3.0%的TAVR患者发生中风(Χ² P = 0.71)。在接受MIAVR的患者中,5.4%术后需要植入永久性起搏器,而TAVR患者为14%(Χ² P = 0.04)。轻度瓣周漏(PVL)影响2.2%的MIAVR患者和28%的TAVR患者,中度PVL在2.2%的MIAVR患者和3%的TAVR患者中报告(Χ² P < 0.001)。

结论

VAMC心脏团队为患有孤立性主动脉瓣疾病的退伍军人提供MIAVR和TAVR,尽管病例数量相对较少,但取得了优异的结果。两者均提供出色的血流动力学结果,在复杂人群中的死亡率较低。