Center for Salivary Diagnostics, Hyposalivation and Halitosis, University Center for Dental Medicine Basel UZB, University of Basel, Basel, Switzerland.
Swiss Dent J. 2024 Jun 12;134(3):18-34. doi: 10.61872/sdj-2024-03-09.
This study investigated and compared the consistency and compressive strength of two commercially available paraffin wax chewing gums (Aurosan (AU) and GC Europe (GC)), as well as their impact on stimulated salivary flow rate. Instrumental texture analysis was uti-lized to assess the consistency and compressive strength of AU and GC during a 7-min chewing period. Subsequently, stimulated salivary flow rate (sSFR) was evaluated in healthy subjects using AU and GC over a 7-minute period. The compressive strengths from the pre-liminary test were compared over time with the sialometry data. Eighty-one test subjects, comprising 33 men and 48 women, participated. Over the 7-min measurement period, dif-ferences were observed in the total amount of saliva accumulated per minute. Direct com-parison of AU and GC revealed that regardless of age and gender, the amount of saliva formed after 1 min was 0.63 times less with AU than with GC (95% CI: 0.56 - 0.70; P < 0.001). The accumulated saliva volume with AU was also significantly lower than that with GC in the first 4 min (P = 0.016). However, from minute 5 onwards, the two products no longer showed statistical differences in the total amount of saliva. Comparison of the com-pressive strength of AU and GC showed that the values after 1 and 2 min were significantly higher for AU than for GC (P < 0.05); for all other time points, the compressive strength was higher for GC. In the mixed-effects model after log-transformation of compressive strength and saliva volume, GC exhibited decreasing saliva volumes with increasing compressive strength (P <0.001). Conversely, the opposite was observed for AU (P = 0.019). The study suggests that the consistency or compressive strength of paraffin wax chewing gums from different manufacturers could impact sSFR.
本研究调查并比较了两种市售的石蜡基口香糖(Aurosan(AU)和 GC Europe(GC))的一致性和抗压强度,以及它们对刺激唾液流量的影响。利用仪器质地分析评估 AU 和 GC 在 7 分钟咀嚼期间的一致性和抗压强度。随后,在 7 分钟内使用 AU 和 GC 评估健康受试者的刺激唾液流量(sSFR)。将初步测试中的抗压强度与唾液流量数据进行比较。共有 81 名测试对象参加,包括 33 名男性和 48 名女性。在 7 分钟的测量期间,每分钟累积的唾液总量存在差异。AU 和 GC 的直接比较表明,无论年龄和性别如何,AU 在 1 分钟后形成的唾液量比 GC 少 0.63 倍(95%CI:0.56-0.70;P<0.001)。AU 的累积唾液量在前 4 分钟也明显低于 GC(P=0.016)。然而,从第 5 分钟开始,两种产品在总唾液量上不再表现出统计学差异。AU 和 GC 的抗压强度比较表明,AU 在 1 分钟和 2 分钟后的数值显著高于 GC(P<0.05);对于所有其他时间点,GC 的抗压强度更高。在对数转换后的抗压强度和唾液量的混合效应模型中,GC 表现出随着抗压强度的增加唾液量减少(P<0.001)。相反,AU 则相反(P=0.019)。该研究表明,来自不同制造商的石蜡基口香糖的一致性或抗压强度可能会影响 sSFR。