Department of Psychiatry and Behavioral Medicine, Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
AIDS Patient Care STDS. 2024 Jun;38(6):267-274. doi: 10.1089/apc.2024.0012. Epub 2024 Jun 12.
Human immunodeficiency virus (HIV) is a public health concern among young sexual minority men (YSMM), ages 17 to 24, in the United States. Biomedical prevention methods, such as pre-exposure prophylaxis (PrEP) and non-occupational post-exposure prophylaxis (nPEP), can help reduce the risk of HIV transmission among this population. However, there is limited awareness and use of nPEP by YSMM. This study aims to explore the perceptions of YSMM regarding the nPEP care continuum, which consists of three areas of focus: awareness, uptake, and linkage to other HIV prevention services. This study draws on synchronous online focus groups with a sample of 41 YSMM in the United States. Transcripts from the focus groups were analyzed using reflexive thematic analysis. Participants reported limited nPEP awareness and prior use, a process of personal appraisal of nPEP need based on HIV risk and costs, and a preference for PrEP over PEP for long-term HIV prevention. Interventions should be tailored to increase awareness of nPEP among YSMM and reduce addressable barriers to nPEP use for YSMM, including cost and confidentiality concerns, in situations where nPEP is warranted. Finally, more research is needed on how nPEP use can act as a bridge to PrEP initiation for this population.
人类免疫缺陷病毒(HIV)是美国 17 至 24 岁青年性少数群体男性(YSMM)的公共卫生关注问题。生物医学预防方法,如暴露前预防(PrEP)和非职业性暴露后预防(nPEP),可以帮助降低该人群中 HIV 传播的风险。然而,YSMM 对 nPEP 的知晓率和使用率有限。本研究旨在探讨 YSMM 对 nPEP 护理连续体的看法,该连续体由三个重点领域组成:知晓率、使用率和与其他 HIV 预防服务的联系。本研究借鉴了在美国进行的 41 名 YSMM 同步在线焦点小组的资料。使用反思性主题分析对焦点小组的记录进行了分析。参与者报告了对 nPEP 的认识有限且以前曾使用过,他们根据 HIV 风险和成本对 nPEP 的需求进行个人评估的过程,以及对 PrEP 而非 PEP 用于长期 HIV 预防的偏好。干预措施应根据需要调整,以提高 YSMM 对 nPEP 的认识,并减少 nPEP 使用的可解决障碍,包括成本和保密性问题。最后,需要更多研究了解 nPEP 的使用如何作为该人群开始使用 PrEP 的桥梁。
Arch Public Health. 2023-6-21
AIDS Patient Care STDS. 2022-10