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Fixed ratio combination of propranolol and bendrofluazide in the treatment of hypertension.

作者信息

Pandhi P, Sharma B K, Sharma P L, Wahi P L

出版信息

Int J Clin Pharmacol Ther Toxicol. 1985 Feb;23(2):92-4.

PMID:3886568
Abstract

The combination of beta adrenoceptor blocker, i.e. propranolol (80 mg) and a diuretic, i.e. bendrofluazide (2.5 mg) in a single capsule (Inderetic) produced an effective control of blood pressure in 12 out of 13 patients with mild and moderately severe hypertension in this single-blind study. Treatment for 12 weeks did not produce any changes in biochemical parameters and no change in ECG, except that a significant decrease in heart rate was observed. No serious side-effects were observed.

摘要

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