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使用非侵入性技术评估人体皮肤光散射特性与年龄的相关性。

Correlations of light scattering properties in human skin with the person's age assessed using a non-invasive technique.

作者信息

Golmajer Zima Neža, Verdel Nina, Majaron Boris

机构信息

Department of Complex Matter, Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.

Faculty of Mathematics and Physics, University of Ljubljana, Jadranska 19, 1000 Ljubljana, Slovenia.

出版信息

Biomed Opt Express. 2024 May 20;15(6):3817-3830. doi: 10.1364/BOE.523183. eCollection 2024 Jun 1.

DOI:10.1364/BOE.523183
PMID:38867783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11166447/
Abstract

We analyze the influence of a person's age on the thicknesses and reduced scattering coefficients of the epidermis and dermis in visible part of the spectrum. Their values were assessed using a non-invasive technique which combines pulsed photothermal radiometry and diffuse reflectance spectroscopy with Monte Carlo modeling of light transport in a four-layer model of skin. The analysis is affected by the strong influences of the melanin content on the reduced scattering coefficient of the epidermis, , and blood content in the case of dermis ( ). Separating their contributions reveals a significant decrease of with the person's age at an average rate of -0.25 mm per decade, while the contribution of blood in the papillary dermis amounts to 1.0 mm%. Meanwhile, no influence of the person's age was found on and the thicknesses of the epidermis or dermis.

摘要

我们分析了一个人的年龄对光谱可见部分表皮和真皮厚度及约化散射系数的影响。使用一种非侵入性技术评估其值，该技术将脉冲光热辐射测量法和漫反射光谱法与皮肤四层模型中光传输的蒙特卡罗建模相结合。黑色素含量对表皮约化散射系数（ ）有强烈影响，而真皮情况（ ）下血液含量有强烈影响，这会影响分析。分离它们的贡献显示， 随人的年龄显著下降，平均速率为每十年 -0.25 mm，而乳头层真皮中血液的贡献为1.0 mm%。同时，未发现人的年龄对 以及表皮或真皮厚度有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/110804102f48/boe-15-6-3817-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/99cc0225c36f/boe-15-6-3817-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/95b2c998aa7b/boe-15-6-3817-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/e5f7e52bd9ca/boe-15-6-3817-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/6c844e5594de/boe-15-6-3817-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/9a0bb2ae55b5/boe-15-6-3817-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/3a4720b0a019/boe-15-6-3817-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/110804102f48/boe-15-6-3817-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/99cc0225c36f/boe-15-6-3817-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/ad19d18a686e/boe-15-6-3817-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/1b53a557b3ec/boe-15-6-3817-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/5d8f9aa48d3c/boe-15-6-3817-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/367527dce55b/boe-15-6-3817-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/95b2c998aa7b/boe-15-6-3817-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/e5f7e52bd9ca/boe-15-6-3817-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/6c844e5594de/boe-15-6-3817-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/9a0bb2ae55b5/boe-15-6-3817-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/3a4720b0a019/boe-15-6-3817-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1166/11166447/110804102f48/boe-15-6-3817-g011.jpg

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