Yu Hang, Zhao Hongguo, Liu Dongxia, Dong Yanhua, Nai Manman, Song Yikun, Liu Jiaxi, Wang Luwen, Li Lei, Li Xinbin
The Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, PR China.
School of Marine Science and Technology, Northwestern Polytechnical University, Xi'an, 710072, PR China.
Heliyon. 2024 May 27;10(11):e31928. doi: 10.1016/j.heliyon.2024.e31928. eCollection 2024 Jun 15.
The objective is to construct a random forest model for predicting the occurrence of Myofascial pelvic pain syndrome (MPPS) and compare its performance with a logistic regression model to demonstrate the superiority of the random forest model.
We retrospectively analyze the clinical data of female patients who underwent pelvic floor screening due to chronic pelvic pain at the Pelvic Floor Rehabilitation Center of the Third Affiliated Hospital of Zhengzhou University from January 2021 to December 2023. A total of 543 female patients meeting the study's inclusion and exclusion criteria are randomly selected from this dataset and allocated to the MPPS group. Furthermore, 702 healthy female patients who underwent pelvic floor screening during routine physical examinations within the same timeframe are randomly selected and assigned to the non-MPPS group. Chi-square test and rank-sum test are used to select demographic variables, pelvic floor pressure assessment data variables, and modified Oxford muscle strength grading data for logistic univariate analysis. The selected variables are further subjected to multivariate logistic regression analysis, and a random forest model is also established. The predictive performance of the two models is evaluated by comparing their accuracy, sensitivity, specificity, precision, receiver operating characteristic (ROC) curve, and area under the curve (AUC) area.
Based on a dataset of 1245 cases, we implement the random forest algorithm for the first time in the screening of MPPS. In this investigation, the Logistic regression model forecasts the accuracy, sensitivity, specificity, and precision of MPPS at 69.96 %, 57.46 %, 79.63 %, and 68.57 % respectively, with an AUC of the ROC curve at 0.755. Conversely, the random forest prediction model exhibits accuracy, sensitivity, specificity, and precision rates of 87.11 %, 90.66 %, 90.91 %, and 83.51 % respectively, with an AUC of the ROC curve at 0.942. The random forest model showcases exceptional predictive performance during the initial screening of MPPS.
The random forest model has exhibited exceptional predictive performance in the initial screening evaluation of MPPS disease. The development of this predictive framework holds significant importance in refining the precision of MPPS prediction within clinical environments and elevating treatment outcomes. This research carries profound global implications, given the potentially elevated misdiagnosis rates and delayed diagnosis proportions of MPPS on a worldwide scale, coupled with a potential scarcity of seasoned healthcare providers. Moving forward, continual refinement and validation of the model will be imperative to further augment the precision of MPPS risk assessment, thereby furnishing clinicians with more dependable decision-making support in clinical practice.
构建用于预测肌筋膜性盆腔疼痛综合征(MPPS)发生的随机森林模型,并将其性能与逻辑回归模型进行比较,以证明随机森林模型的优越性。
回顾性分析2021年1月至2023年12月在郑州大学第三附属医院盆底康复中心因慢性盆腔疼痛接受盆底筛查的女性患者的临床资料。从该数据集中随机选取543例符合研究纳入和排除标准的女性患者,分配至MPPS组。此外,随机选取同一时间段内702例在常规体检中接受盆底筛查的健康女性患者,分配至非MPPS组。采用卡方检验和秩和检验选择人口统计学变量、盆底压力评估数据变量以及改良牛津肌力分级数据进行逻辑单因素分析。将所选变量进一步进行多因素逻辑回归分析,并建立随机森林模型。通过比较两种模型的准确性、敏感性、特异性、精确性、受试者工作特征(ROC)曲线及曲线下面积(AUC)来评估两种模型的预测性能。
基于1245例病例的数据集,我们首次在MPPS筛查中实施随机森林算法。在本次研究中,逻辑回归模型预测MPPS的准确性、敏感性、特异性和精确性分别为69.96%、57.46%、79.63%和68.57%,ROC曲线的AUC为0.755。相反,随机森林预测模型的准确性、敏感性、特异性和精确性分别为87.11%、90.66%、90.91%和83.51%,ROC曲线的AUC为0.942。随机森林模型在MPPS的初步筛查中表现出卓越的预测性能。
随机森林模型在MPPS疾病的初步筛查评估中表现出卓越的预测性能。这一预测框架的开发对于提高临床环境中MPPS预测的准确性以及改善治疗效果具有重要意义。鉴于全球范围内MPPS的误诊率和延迟诊断比例可能较高,且经验丰富的医疗服务提供者可能短缺,本研究具有深远的全球意义。展望未来,持续改进和验证该模型对于进一步提高MPPS风险评估的准确性至关重要,从而为临床医生在临床实践中提供更可靠的决策支持。