一名接受抗凝治疗的HIV感染患者发生深静脉血栓形成的病例。
A Case of Deep Venous Thrombosis in an HIV-Infected Patient despite Therapeutic Anticoagulation.
作者信息
Aiman Wajeeha, Ali Muhammad Ashar, Grewal Navjot, Bethel Nyan, Savopoulos Andreas A, Guron Gunwant
机构信息
Saint Michael's Medical Center, New York College of Medicine, Newark, NJ, USA.
Saint Clare's and St. Mary's General Hospital, Denville, NJ, USA.
出版信息
Int J Hematol Oncol Stem Cell Res. 2024 Apr 1;18(2):206-209. doi: 10.18502/ijhoscr.v18i2.15379.
Patients with human immunodeficiency virus (HIV) infection have an increased likelihood of venous thromboembolism (VTE) owing to factors such as acquired protein C and S deficiency, antiphospholipid antibody syndrome, and heightened levels of pro-inflammatory cytokines. This case report highlights an exceptionally uncommon occurrence of deep venous thrombosis in an HIV-infected patient receiving a therapeutic dose of enoxaparin. This underscores the need for cautious consideration of the risk of VTE in HIV-infected individuals, even with preventive or therapeutic anticoagulant treatment. Further research is recommended to investigate HIV as a potential risk factor of prophylactic anticoagulation.
由于获得性蛋白C和S缺乏、抗磷脂抗体综合征以及促炎细胞因子水平升高，人类免疫缺陷病毒（HIV）感染患者发生静脉血栓栓塞（VTE）的可能性增加。本病例报告强调了在接受治疗剂量依诺肝素的HIV感染患者中发生深静脉血栓形成这一极为罕见的情况。这突出了即使在进行预防性或治疗性抗凝治疗时，也需要谨慎考虑HIV感染个体发生VTE的风险。建议进一步开展研究，以调查HIV作为预防性抗凝潜在风险因素的情况。
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