Krajewski Piotr K, Strobel Alexandra, Schultheis Michael, Staubach Petra, Grabbe Stephan, Hennig Katharina, Matusiak Lukasz, von Stebut Esther, Garcovich Simone, Bayer Hans, Heise Marcus, Kirschner Uwe, Nikolakis Georgios, Szepietowski Jacek C
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chalubinskiego 1, 50-368, Wroclaw, Poland.
Faculty of Medicine, Institute of Medical Epidemiology, Biostatistics, and Informatics, Martin Luther University Halle-Wittenberg, Saale, Halle, Germany.
Dermatol Ther (Heidelb). 2024 Jul;14(7):1823-1838. doi: 10.1007/s13555-024-01196-y. Epub 2024 Jun 13.
Sexual health, a critical aspect of overall well-being, is often compromised in individuals with chronic disorders. Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that mainly affects intertriginous areas, potentially impacting sexual health as a result of its specific symptoms and psychosocial burden.
This cross-sectional study utilized data from the EpiCAi project, focusing on 199 patients with HS. Participants completed digital questionnaires assessing sexual health via sex-specific instruments: the Female Sexual Function Index (FSFI) for women and the International Index of Erectile Function (IIEF) for men, alongside different psychosocial scales. The disease severity was assessed using the Hurley stage and the Lesion Identification Scheme for Acne Inversa (LISAI).
The majority of the participants reported impaired sexual health, with significant clinical sexual dysfunctions noted in 71.8% of women (FSFI score < 26) and erectile dysfunction in 63.8% of men. Sexual dysfunction was associated with several factors, including age, and marital status. Psychosocial factors, notably depression and quality of life, showed strong correlations with sexual health outcomes. Notably, women over 40 and those treated with biologics reported more severe dysfunction, while among men, employment status significantly influenced sexual health.
HS profoundly affects the sexual health of both male and female patients, with significant impacts on their quality of life and psychological well-being. The findings underscore the necessity for healthcare providers to address sexual health proactively in the management of HS, considering both physical symptoms and psychosocial impacts. This holistic approach is essential for improving patient outcomes and overall quality of life.
German Register for Clinical Trials, identifier DRKS00025315.
性健康是整体健康的一个关键方面,在患有慢性疾病的个体中常常受到损害。化脓性汗腺炎(HS)是一种慢性炎症性皮肤病,主要影响皮肤褶皱部位,由于其特定症状和心理社会负担,可能会对性健康产生影响。
这项横断面研究利用了EpiCAi项目的数据,重点关注199名HS患者。参与者通过针对性别的工具完成了评估性健康的数字问卷:女性使用女性性功能指数(FSFI),男性使用国际勃起功能指数(IIEF),同时还包括不同的心理社会量表。使用赫尔利分期和反向痤疮病变识别方案(LISAI)评估疾病严重程度。
大多数参与者报告性健康受损,71.8%的女性(FSFI评分<26)存在明显的临床性功能障碍,63.8%的男性存在勃起功能障碍。性功能障碍与几个因素相关,包括年龄和婚姻状况。心理社会因素,特别是抑郁和生活质量,与性健康结果显示出强烈的相关性。值得注意的是,40岁以上的女性和接受生物制剂治疗的女性报告的功能障碍更严重,而在男性中,就业状况对性健康有显著影响。
HS对男性和女性患者的性健康都有深远影响,对他们的生活质量和心理健康产生重大影响。研究结果强调了医疗保健提供者在HS管理中积极解决性健康问题的必要性,要同时考虑身体症状和心理社会影响。这种整体方法对于改善患者预后和整体生活质量至关重要。
德国临床试验注册中心,标识符DRKS00025315。