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白癜风与性功能障碍的关联:现有证据。

Association between vitiligo and sexual dysfunction: current evidence.

机构信息

Chinese medicine department, Songnan Town Community Health Service Center, Shanghai, China.

Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

出版信息

Ann Med. 2023 Dec;55(1):946-953. doi: 10.1080/07853890.2023.2182906.

DOI:10.1080/07853890.2023.2182906
PMID:36892992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10795651/
Abstract

BACKGROUND

We discovered that vitiligo was associated with sexual dysfunction in clinical diagnosis and treatment; however, no further analysis had been performed due to a lack of data.

OBJECTIVE

This study aimed to clarify the relationship between vitiligo and sexual dysfunction.

METHODS

We searched six databases (PubMed, Embase, Cochrane, China National Knowledge Infrastructure, China Science and Technology Journal, and Wanfang Data Knowledge Service Platform) for nearly 40 years.

RESULTS

According to the search strategy, 91 relevant studies were retrieved, of which 4 were included in the analysis. The Arizona Sexual Experience Scale (ASEX) score (mean difference [MD] 4.96, 95% confidence interval [CI] 2.78-7.13,  < 0.00001) was higher in the vitiligo group than in the control group. The Arabic version of the Female Sexual Function Index (AVFSFI) score (mean difference [MD] - 3.40, 95% confidence interval [CI] - 5.49 to -1.31,  = 0.001) was lower in the vitiligo group than in the control group.

CONCLUSIONS

Patients with vitiligo were found to be at greater risk of sexual dysfunction. Moreover, the association between vitiligo and sexual dysfunction was stronger in women than in men.Key MessagesPatients with vitiligo were found to be at greater risk of sexual dysfunction.The association between vitiligo and sexual dysfunction was stronger in women than in men.

摘要

背景

我们在临床诊断和治疗中发现,白癜风与性功能障碍有关;但是,由于缺乏数据,没有进一步分析。

目的

本研究旨在阐明白癜风与性功能障碍之间的关系。

方法

我们在六个数据库(PubMed、Embase、Cochrane、中国知网、中国科技期刊数据库和万方数据知识服务平台)中搜索了近 40 年的数据。

结果

根据检索策略,共检索到 91 篇相关研究,其中 4 篇纳入分析。白癜风组的亚利桑那性体验量表(ASEX)评分(均数差 [MD] 4.96,95%置信区间 [CI] 2.78-7.13,  < 0.00001)高于对照组。阿拉伯版女性性功能指数(AVFSFI)评分(MD  - 3.40,95%置信区间 [CI]  - 5.49 至 -1.31,  = 0.001)低于对照组。

结论

白癜风患者发生性功能障碍的风险更高。此外,白癜风与性功能障碍之间的关联在女性中比在男性中更强。

关键信息

  1. 白癜风患者发生性功能障碍的风险更高。

  2. 白癜风与性功能障碍之间的关联在女性中比在男性中更强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/846b/10795651/f3f7d2a68595/IANN_A_2182906_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/846b/10795651/f3f7d2a68595/IANN_A_2182906_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/846b/10795651/f3f7d2a68595/IANN_A_2182906_F0001_C.jpg

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2
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Clin Exp Dermatol. 2021 Jun;46(4):669-674. doi: 10.1111/ced.14511. Epub 2020 Dec 18.
3
Urinary metabolomic investigations in vitiligo patients.
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Int J Environ Res Public Health. 2025 Jan 24;22(2):157. doi: 10.3390/ijerph22020157.
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Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia.CLT4A变体作为免疫调节分子在沙特阿拉伯白癜风患者中的疗效。
Sci Rep. 2025 Feb 5;15(1):4407. doi: 10.1038/s41598-025-88749-z.
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Healthy lifestyle choices: new insights into vitiligo management.健康的生活方式选择:白癜风管理的新见解。
Front Immunol. 2024 Nov 18;15:1440705. doi: 10.3389/fimmu.2024.1440705. eCollection 2024.
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Dermatol Ther (Heidelb). 2024 Jul;14(7):1823-1838. doi: 10.1007/s13555-024-01196-y. Epub 2024 Jun 13.
白癜风患者的尿液代谢组学研究。
Sci Rep. 2020 Oct 22;10(1):17989. doi: 10.1038/s41598-020-75135-0.
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