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尼日利亚抗逆转录病毒疗法不依从性及其与社会心理因素的关联:对感染艾滋病毒的性少数群体和异性恋男性的比较研究。

Antiretroviral therapy non-adherence and its association with psychosocial factors in Nigeria: comparative study of sexual minority and heterosexual men living with HIV.

作者信息

Oginni Olakunle Ayokunmi, Adelola Aderopo Igbekeleoluwa, Ogunbajo Adedotun, Opara Onyedikachi Joseph, Akanji Michael, Ibigbami Olanrewaju Ibikunle, Afolabi Olusegun Temitope, Akinsulore Adesanmi, Mapayi Boladale Moyosore, Mosaku Samuel Kolawole

机构信息

Department of Mental Health, Obafemi Awolowo University, Ile-Ife, Nigeria.

Department of Mental Health, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.

出版信息

AIDS Care. 2024 Oct;36(10):1369-1381. doi: 10.1080/09540121.2024.2366511. Epub 2024 Jun 13.

Abstract

Sexual minority men (gay, bisexual and other men who have sex with men; SMM) in Nigeria are disproportionately affected by HIV compared to heterosexual men. There is a dearth of research on the correlates of antiretroviral therapy (ART) non-adherence and correlates in both groups. The current study examined the associations of ART non-adherence with sociodemographic and psychosocial characteristics among a sample of Nigerian heterosexual and SMM. Between March and September 2014, we surveyed 120 SMM and 108 heterosexual men receiving ART in Lagos and Abuja, Nigeria. We specified univariate and multivariable linear regression models to examine correlates of ART non-adherence. We found that 50.8% and 29.6% of sexual minority and heterosexual men respectively self-reported ART non-adherence which was significantly associated with psychosocial factors such as stigma, depressive symptoms, and suicidality. Mental health care and psychosocial support should be incorporated into routine HIV care for Nigerian SMM living with HIV.

摘要

与异性恋男性相比,尼日利亚的性少数群体男性(男同性恋者、双性恋者及其他与男性发生性行为的男性;SMM)受艾滋病毒影响的比例过高。关于抗逆转录病毒疗法(ART)不依从性的相关因素以及这两组人群的相关因素,研究非常匮乏。本研究调查了尼日利亚异性恋和性少数群体男性样本中ART不依从性与社会人口学及心理社会特征之间的关联。2014年3月至9月期间,我们对尼日利亚拉各斯和阿布贾接受ART治疗的120名性少数群体男性和108名异性恋男性进行了调查。我们指定了单变量和多变量线性回归模型来研究ART不依从性的相关因素。我们发现,分别有50.8%的性少数群体男性和29.6%的异性恋男性自我报告存在ART不依从性,这与耻辱感、抑郁症状和自杀倾向等心理社会因素显著相关。心理健康护理和心理社会支持应纳入为感染艾滋病毒的尼日利亚性少数群体男性提供的常规艾滋病毒护理中。

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