McNabb Lorna, Metrot Eva, Ferrington Micaela, Sunderland Bruce, Parsons Richard, Copeland Tandy-Sue, Corscadden Siobhan, Tong Selina, Czarniak Petra
Curtin Medical School, Faculty of Health Sciences, Curtin University, Bentley, Western Australia, Australia.
Pharmacy Department, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
PLoS One. 2024 Jun 13;19(6):e0304011. doi: 10.1371/journal.pone.0304011. eCollection 2024.
Oral antineoplastic agents have caused a paradigm shift in cancer treatment, however, they produce many unique challenges. Although oral antineoplastics can have complex administration regimes, low adherence rates and high possibilities of drug-drug interactions, they are administered unsupervised at home. Cancer services pharmacists have the required skillsets to improve patient outcomes associated with oral antineoplastic treatment by increasing patient health literacy, improving concordance and optimising administration protocols.
To evaluate patients' perceptions, experiences and overall satisfaction with dedicated clinical pharmacist consultations in patients treated with oral antineoplastic agents at a major public hospital.
In this retrospective cross-sectional study at a quaternary hospital in Western Australia, data were collected by a paper questionnaire (mailed in March 2022) to a random sample of 191 patients initiated on oral antineoplastic drugs between January 2021 and February 2022. Demographics, prescribed antineoplastic drug/s, cancer type data were collected including using 5-point Likert scale questions assess patients' overall satisfaction with the clinical pharmacist consultations.
The questionnaire response rate was 27.7% (52/188) (mean age 63.2 years; 57.5% female). Most patients (42/52; 80.8%) were satisfied with pharmacist consultations, trusted the pharmacist's advice (45/52; 86.5%), considered that the pharmacist improved their understanding of how to manage side effects (43/52; 82.7%) and they provided an important service in outpatient care (45/52; 86.5%).
Overall, patients reported positive perceptions, experiences, and satisfaction with the cancer services pharmacist counselling services during their oral antineoplastic treatment.
口服抗肿瘤药物在癌症治疗领域引发了一场范式转变，然而，它们也带来了许多独特的挑战。尽管口服抗肿瘤药物的给药方案可能很复杂，患者依从率低且药物相互作用的可能性高，但这些药物是患者在家中自行服用，无人监督。癌症服务药剂师具备必要的技能组合，可通过提高患者健康素养、改善依从性和优化给药方案，来改善与口服抗肿瘤治疗相关的患者治疗效果。
评估在一家大型公立医院接受口服抗肿瘤药物治疗的患者对专门的临床药剂师咨询服务的看法、体验和总体满意度。
在西澳大利亚一家四级医院进行的这项回顾性横断面研究中，通过纸质问卷（于2022年3月邮寄）收集了2021年1月至2022年2月期间开始使用口服抗肿瘤药物的191名患者的随机样本数据。收集了人口统计学信息、处方的抗肿瘤药物、癌症类型数据，包括使用5点李克特量表问题来评估患者对临床药剂师咨询服务的总体满意度。
问卷回复率为27.7%（52/188）（平均年龄63.2岁；57.5%为女性）。大多数患者（42/52；80.8%）对药剂师的咨询服务感到满意，信任药剂师的建议（45/52；86.5%），认为药剂师增进了他们对如何管理副作用的理解（43/52；82.7%），并且认为药剂师在门诊护理中提供了重要服务（45/52；86.5%）。
总体而言，患者在口服抗肿瘤治疗期间对癌症服务药剂师的咨询服务给出了积极的看法、体验和满意度。
