Department of Hyperbaric Medicine, Fiona Stanley Hospital, Perth, Australia.
Corresponding author: Dr John Currie, Department of Hyperbaric Medicine, Fiona Stanley Hospital, 102-118 Murdoch Drive, Murdoch WA 6150, Australia, ORCiD: 0009-0009-0086-4953,
Diving Hyperb Med. 2024 Jun 30;54(2):92-96. doi: 10.28920/dhm54.2.92-96.
Avascular necrosis (AVN) is a rare progressive degenerative disease leading to bone and joint destruction. Patients often require surgical intervention. Femoral AVN is the most common anatomical location. Hyperbaric oxygen treatment (HBOT) has been shown to be effective in AVN. We present data collected from one centre over a 30-year period and compare the results with other published data.
A retrospective chart review of all patients receiving HBOT for AVN at Fremantle and Fiona Stanley Hospitals since 1989 was performed. The primary outcome was radiological appearance using the Steinberg score, with secondary outcomes being subjective improvement, the need for joint replacement surgery and rates of complications.
Twenty-one joints in 14 patients (14 femoral heads and seven femoral condyles) were treated with HBOT since 1989. Two patients were excluded. Within the femoral head group, nine of the 14 joints (64%) had stable or improved magnetic resonance imaging (MRI) scans post treatment and at six months (minimum); 10 joints (71%) had good outcomes subjectively, three joints required surgical intervention, and three patients developed mild aural barotrauma. Within the femoral condyle group, all five joints had stable or improved post-treatment MRI scans (four had visible improvement in oedema and/or chondral stability), four joints reported good outcomes subjectively, none of the patients required surgical intervention (follow-up > six months).
This single centre retrospective study observed prevention of disease progression in femoral AVN with the use of HBOT, comparable to other published studies. This adds to the body of evidence that HBOT may have a significant role in the treatment of femoral AVN.
缺血性坏死(AVN)是一种罕见的进行性退行性疾病,可导致骨骼和关节破坏。患者通常需要手术干预。股骨 AVN 是最常见的解剖部位。高压氧治疗(HBOT)已被证明对 AVN 有效。我们提供了 30 年来从一个中心收集的数据,并将结果与其他已发表的数据进行了比较。
对自 1989 年以来 Fremantle 和 Fiona Stanley 医院因 AVN 接受 HBOT 的所有患者进行了回顾性图表审查。主要结果是采用 Steinberg 评分的影像学表现,次要结果是主观改善、关节置换手术的需要以及并发症发生率。
自 1989 年以来,14 名患者的 21 个关节(14 个股骨头和 7 个股骨髁)接受了 HBOT 治疗。排除了两名患者。在股骨头组中,14 个关节中的 9 个(64%)在治疗后和 6 个月(最短)时的磁共振成像(MRI)扫描稳定或改善;10 个关节(71%)主观上有良好的结果,3 个关节需要手术干预,3 名患者出现轻度耳气压伤。在股骨髁组中,所有 5 个关节的治疗后 MRI 扫描均稳定或改善(4 个关节的水肿和/或软骨稳定性可见改善),4 个关节主观上报告良好的结果,没有患者需要手术干预(随访>6 个月)。
这项单中心回顾性研究观察到 HBOT 可预防股骨 AVN 疾病进展,与其他已发表的研究相似。这增加了 HBOT 在治疗股骨 AVN 方面可能具有重要作用的证据。