Suppr超能文献

高压氧与髓芯减压治疗轻度至中度股骨头缺血性坏死的回顾性比较

A retrospective comparison of hyperbaric oxygen and core decompression for mild to moderate avascular necrosis of the femoral head.

作者信息

Sun Ming, Liang Hairui, Chen Yong, Duan Siyu, Xu Rongda, Cai Zhencun

机构信息

Department of Orthopedics Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, Liaoning Province, China.

Department of Orthopedic Surgery, Central Hospital Affiliated to Shenyang Medical College, Shenyang, Liaoning Province, China.

出版信息

Med Gas Res. 2026 Mar 1;16(1):1-5. doi: 10.4103/mgr.MEDGASRES-D-24-00162. Epub 2025 Jun 28.

Abstract

JOURNAL/mgres/04.03/01612956-202603000-00001/figure1/v/2025-06-28T140100Z/r/image-tiff Avascular necrosis of the femoral head is a condition resulting from disrupted blood supply, leading to ischemia and bone tissue necrosis. Core decompression (CD) restores the blood supply through pressure relief, whereas hyperbaric oxygen (HBO) enhances tissue oxygenation and promotes bone repair. Their combined use may complement each other in improving blood supply, promoting bone healing, and inhibiting disease progression, thus achieving a better therapeutic effect. To assess and compare the efficacy of HBO and/or CD for treating mild to moderate femoral head avascular necrosis, a retrospective study was conducted on patients diagnosed with Ficat stage II non-traumatic osteonecrosis between January 2017 and January 2022 at the Affiliated Central Hospital of Shenyang Medical University, China. A total of 72 patients were divided into HBO, CD, and combination groups, with 24 patients in each group. After 1 year of follow-up, 90% of patients in the HBO group, 85% in the CD group, and 95% in the combination group showed satisfactory improvements in hip joint function. The SF-36 quality of life questionnaire scale scores also significantly improved in all three groups, with the combination group showing the most significant improvement. These findings suggest that HBO offers promising potential for treating non-traumatic femoral head necrosis, with efficacy similar to that of CD. The combination group showed the most significant improvement in both hip joint function and quality of life.

摘要

《mgres》/04.03/01612956 - 202603000 - 00001/figure1/v/2025 - 06 - 28T140100Z/r/image - tiff 股骨头缺血性坏死是一种由于血液供应中断导致缺血和骨组织坏死的病症。髓芯减压术(CD)通过减压来恢复血液供应,而高压氧(HBO)可增强组织氧合并促进骨修复。它们联合使用在改善血液供应、促进骨愈合以及抑制疾病进展方面可能会起到互补作用,从而取得更好的治疗效果。为了评估和比较HBO和/或CD治疗轻度至中度股骨头缺血性坏死的疗效,对2017年1月至2022年1月在中国沈阳医学院附属中心医院被诊断为Ficat II期非创伤性骨坏死的患者进行了一项回顾性研究。总共72例患者被分为HBO组、CD组和联合治疗组,每组24例。经过1年的随访,HBO组90%的患者、CD组85%的患者以及联合治疗组95%的患者髋关节功能均有令人满意的改善。所有三组的SF - 36生活质量问卷量表评分也均显著提高,联合治疗组的改善最为显著。这些结果表明,HBO在治疗非创伤性股骨头坏死方面具有广阔的潜力,其疗效与CD相似。联合治疗组在髋关节功能和生活质量方面的改善最为显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d90/12318576/79a608587980/MGR-16-1-g002.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验