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输尿管诊断性腔内超声与光学相干断层扫描的当代现状

Contemporary status of diagnostic endoluminal ultrasound and optical coherence tomography in the ureter.

作者信息

Sii Samuel, Bolton Jeremy, Tempo Jake, Bolton Damien

机构信息

Department of Surgery University of Melbourne, Austin Health Melbourne Victoria Australia.

Monash University Melbourne Victoria Australia.

出版信息

BJUI Compass. 2024 Mar 19;5(6):514-523. doi: 10.1002/bco2.352. eCollection 2024 Jun.


DOI:10.1002/bco2.352
PMID:38873352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11168776/
Abstract

OBJECTIVE: To evaluate via a review of published literature, the efficacy of endoluminal ultrasound (ELUS) and optical coherence tomography (OCT) in the following ureteric diseases: urolithiasis, upper tract urothelial carcinoma, stricture disease and pelvic-ureteric junction obstruction (PUJO). PATIENTS AND METHODS: Ureteric high-frequency ELUS provides 360° imaging, to a depth of 20 mm, and has been demonstrated to assess ureteric stricture length, degree of fibrosis and aetiology. OCT produces high-quality images with a penetration depth of 2 mm. ELUS has proven to be useful at the time of endopyelotomy for PUJO as it can identify crossing vessels, some not detectable on CT angiography, allowing the urologist to avoid these when making their incision. Ureteric ELUS may be utilised for submucosal ureteric stones as they are highly visible. Endoluminal ultrasound may be deployed in the case of known sub-mucosal urolithiasis when the ureter appears stone-free. It may help identify sub-mucosal stones or stones within diverticulum. RESULTS: Endoluminal ultrasound has been analysed for its use in determining muscle-invasive urothelial carcinoma of the ureter. The PPV for ≥pT2 was only 16.7% in one study of six patients with MIBC and 76.2% in 21 patients with <pT2 disease. Analysis of OCT for staging UTUC during ureteroscopy and biopsy demonstrated sensitivity for tumour invasion of 100% and specificity of 92%, 83% of lesion staging matched with histological analysis. Imaging analysis did not match histology in three patients with large exophytic tumours that exceeded the OCT depth penetration. Due to its superficial penetration, OCT cannot reliably stage large tumours. CONCLUSIONS: Ureteric ELUS has been reported to be a useful tool in endopyelotomy, urolithiasis and stricture disease. The staging of ureteric urothelial carcinoma remains unsatisfactory with current imaging techniques and biopsy methods, and, based on the current literature, ELUS does not appear to have a strong enough PPV to determine muscle invasion. Ureteric OCT may be a useful tool in the future staging of upper tract urothelial carcinoma, particularly in differentiating the stage of small tumours. Further studies are needed in this area.

摘要

目的:通过回顾已发表的文献,评估腔内超声(ELUS)和光学相干断层扫描(OCT)在以下输尿管疾病中的疗效:尿路结石、上尿路尿路上皮癌、狭窄疾病和肾盂输尿管连接处梗阻(PUJO)。 患者和方法:输尿管高频ELUS可提供360°成像,深度达20mm,已被证明可评估输尿管狭窄长度、纤维化程度和病因。OCT可产生高质量图像,穿透深度为2mm。ELUS已被证明在PUJO肾盂切开术时有用,因为它可以识别交叉血管,有些在CT血管造影上无法检测到,使泌尿外科医生在切口时能够避开这些血管。输尿管ELUS可用于粘膜下输尿管结石,因为它们非常明显。当输尿管看起来无结石时,腔内超声可用于已知粘膜下尿路结石的情况。它可能有助于识别粘膜下结石或憩室内的结石。 结果:已分析腔内超声在确定输尿管肌层浸润性尿路上皮癌中的应用。在一项对6例肌层浸润性膀胱癌患者的研究中,≥pT2的阳性预测值仅为16.7%,在21例<pT2疾病患者中为76.2%。在输尿管镜检查和活检期间对OCT进行UTUC分期分析显示,肿瘤浸润的敏感性为100%,特异性为92%,83%的病变分期与组织学分析相符。在3例有大的外生性肿瘤且超过OCT深度穿透范围的患者中,影像学分析与组织学不匹配。由于其浅表穿透性,OCT不能可靠地对大肿瘤进行分期。 结论:据报道,输尿管ELUS在肾盂切开术、尿路结石和狭窄疾病中是一种有用的工具。目前的成像技术和活检方法对输尿管尿路上皮癌的分期仍不令人满意,并且根据目前的文献,ELUS似乎没有足够高的阳性预测值来确定肌层浸润。输尿管OCT可能是未来上尿路尿路上皮癌分期的一种有用工具,特别是在区分小肿瘤的分期方面。该领域需要进一步的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d3f/11168776/112492867265/BCO2-5-514-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d3f/11168776/1232afc0ac85/BCO2-5-514-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d3f/11168776/112492867265/BCO2-5-514-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d3f/11168776/1232afc0ac85/BCO2-5-514-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d3f/11168776/112492867265/BCO2-5-514-g001.jpg

相似文献

[1]
Contemporary status of diagnostic endoluminal ultrasound and optical coherence tomography in the ureter.

BJUI Compass. 2024-3-19

[2]
study in nephroureterectomy specimens defining the role of 3-D upper urinary tract visualization using optical coherence tomography and endoluminal ultrasound.

J Med Imaging (Bellingham). 2018-1

[3]
Accuracy of High-Frequency Endoluminal Ultrasonography for Clinical Staging of Upper Tract Urothelial Carcinoma.

J Endourol. 2018-8-21

[4]
The use of endoluminal ultrasonography for preventing significant bleeding during endopyelotomy: evaluation of helical computed tomography vs endoluminal ultrasonography for detecting crossing vessels.

BJU Int. 2006-4

[5]
Anatomy of ureterovesical junction and distal ureter studied by endoluminal ultrasonography in vitro.

J Urol. 1999-5

[6]
High-frequency endoluminal ultrasonography as an aid to the staging of upper tract urothelial carcinoma: imaging findings and pathologic correlation.

J Ultrasound Med. 2010-9

[7]
Catheter-based intraluminal optical coherence tomography versus endoluminal ultrasonography of porcine ureter ex vivo.

Urology. 2009-6

[8]
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J Urol. 1999-12

[9]
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Urology. 2000-9-1

[10]
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J Urol. 2013-8-13

引用本文的文献

[1]
Erratum.

BJUI Compass. 2024-12-30

本文引用的文献

[1]
CVIT 2023 clinical expert consensus document on intravascular ultrasound.

Cardiovasc Interv Ther. 2024-1

[2]
Prognostic Impact of Operator Experience and IVUS Guidance on Long-Term Clinical Outcomes After Complex PCI.

JACC Cardiovasc Interv. 2023-7-24

[3]
Factors Affecting the Learning Curve in the Endoscopic Ultrasound-Guided Sampling of Solid Pancreatic Lesions: A Prospective Study.

Gut Liver. 2023-3-15

[4]
Intravascular Ultrasound for the Evaluation and Management of Retroperitoneal, Genitourinary Malignancies.

Curr Urol Rep. 2022-5

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Three-Dimensional Intravascular Ultrasound Imaging Using a Miniature Helical Ultrasonic Motor.

IEEE Trans Ultrason Ferroelectr Freq Control. 2022-2

[6]
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Minerva Cardiol Angiol. 2021-12

[7]
Cumulative Sum Analysis for the Learning Curve of Optical Coherence Tomography Assisted Diagnosis of Basal Cell Carcinoma.

Acta Derm Venereol. 2020-12-9

[8]
Applications and future directions for optical coherence tomography in dermatology.

Br J Dermatol. 2021-6

[9]
Advances in IVUS/OCT and Future Clinical Perspective of Novel Hybrid Catheter System in Coronary Imaging.

Front Cardiovasc Med. 2020-7-31

[10]
Bladder, penile, renal pelvis and testis cancers: A population based analysis of incidence and survival 1977-2013.

Cancer Epidemiol. 2020-3-6

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