Central Adelaide Local Health Network, Australia.
Urology Unit, Flinders Medical Centre, Bedford Park, SA, Australia.
Cancer Epidemiol. 2020 Apr;65:101692. doi: 10.1016/j.canep.2020.101692. Epub 2020 Mar 6.
Cancers comprise a significant proportion of urologic workload. The epidemiology of prostate and renal cancers is well described. We report the incidence, survival and predictors of survival for non-prostate, non-renal urologic cancers between 1977 and 2013.
All patients in the South Australian Cancer Registry diagnosed with bladder, testis, penis, renal pelvis, ureteric and other male genital organ cancers between 1977 and 2013 were included. Demographic data included age, sex, year of diagnosis, grade, and metropolitan/rural status. Changes in incidence, survival and predictors of survival are reported for each cancer type.
Between 1977 and 2013, bladder cancer was the most common of the studied urologic cancers (6465/9317). Age standardized incidence rate for bladder cancer decreased from 15.6-9.0 per 100,000 in 2013 (Annual Percentage Change (APC) -0.97 %, p < 0.05 %). Between 1977 and 2013 mortality has increased in patients with bladder cancer (HR 1.01 per year, p = 0.004). Testicular cancer diagnoses increased from 1.7 to 4.7 per 100,000 through 1977-2012 (APC 2.41 %, p < 0.05 %). Survival has increased (HR 0.95 per year, p < 0.001). Incidence of penile cancers has increased from 0.23 to 0.46 per 100,000 (APC 2.8 %); Penile cancer survival has remained static (HR 1.02 p = 0.23).Five and ten year survival estimates were highest for testicular cancer - 93.4 % and 91.1 % respectively; and lowest for renal pelvis - 36.3 % and 24.6 %.
The incidence of non-prostate, non-renal urologic cancers remains low and stable. The age-standardized incidence of testicular cancer has increased whilst there has been a decline in the age-standardized incidence of bladder cancer. Bladder cancer survival has decreased since the 1970s.
癌症占泌尿科工作量的很大一部分。前列腺癌和肾癌的流行病学已得到充分描述。我们报告了 1977 年至 2013 年间非前列腺、非肾脏泌尿科癌症的发病率、生存率和生存率预测因素。
纳入 1977 年至 2013 年间在南澳大利亚癌症登记处诊断为膀胱癌、睾丸癌、阴茎癌、肾盂癌、输尿管癌和其他男性生殖器官癌的所有患者。人口统计学数据包括年龄、性别、诊断年份、分级以及城市/农村状况。报告了每种癌症类型的发病率、生存率和生存率预测因素的变化。
1977 年至 2013 年间，膀胱癌是研究中最常见的泌尿科癌症（6465/9317）。2013 年膀胱癌的年龄标准化发病率从 15.6-9.0/10 万下降（每年百分比变化（APC）-0.97%，p<0.05%）。1977 年至 2013 年间，膀胱癌患者的死亡率有所增加（每年 HR1.01，p=0.004）。1977-2012 年间，睾丸癌的诊断从 1.7 例增加到 4.7 例/10 万（APC2.41%，p<0.05%）。生存率有所提高（每年 HR0.95，p<0.001）。阴茎癌的发病率从 0.23 例增加到 0.46 例/10 万（APC2.8%）；阴茎癌的生存率保持不变（HR1.02，p=0.23）。睾丸癌的 5 年和 10 年生存率估计值最高，分别为 93.4%和 91.1%；肾盂癌的最低，分别为 36.3%和 24.6%。
非前列腺、非肾脏泌尿科癌症的发病率仍然较低且稳定。睾丸癌的年龄标准化发病率增加，而膀胱癌的年龄标准化发病率下降。自 20 世纪 70 年代以来，膀胱癌的生存率有所下降。
