Yoon Na Yeon, Ha Doo Hoe, Lee Sang Min, Choi Hye Jung
J Korean Soc Radiol. 2024 May;85(3):607-617. doi: 10.3348/jksr.2023.0052. Epub 2024 Mar 8.
Recent studies have demonstrated the usefulness of diffusion-weighted MR neurography (DW MRN) for assessing nerve roots. This study aimed to evaluate the utility of DW MRN with a unidirectional motion-probing gradient (MPG) for the lumbar nerve roots at 1.5T MR.
Sixty-four lumbar spine MRI scans with DW MRN using anteroposterior unidirectional MPG were retrospectively analyzed. Any changes in the 512 lumbar spinal nerve roots from L3 to S1 were evaluated using T2-weighted imaging (T2WI), contrast-enhanced T1-weighted imaging (CE T1WI), and DW MRN, with agreement and correlation analysis.
T2WI revealed compression of 78 nerve roots, and CE T1WI revealed 52 instances of nerve root enhancement. Sixty-seven nerve roots showed swelling and hyperintensity on DW MRN. A total of 42 nerve roots showed changes in the CE T1WI and DW MRN sequences. Moderate to substantial agreement and moderate positive correlation were observed between DW MRN and CE T1WI, as well as DW MRN and T2WI (κ = 0.59-0.65, ρ = 0.600-0.653).
DW MRN with unidirectional anteroposterior MPG can help evaluate neuritis-related changes in spinal nerve roots and could serve as a sequence capable of complementing or substituting gadolinium CE imaging.
近期研究已证明扩散加权磁共振神经造影（DW MRN）在评估神经根方面的实用性。本研究旨在评估在1.5T磁共振成像中使用单向运动探测梯度（MPG）的DW MRN对腰神经根的效用。
回顾性分析64例使用前后向单向MPG进行DW MRN的腰椎MRI扫描。使用T2加权成像（T2WI）、对比增强T1加权成像（CE T1WI）和DW MRN评估从L3到S1的512条腰脊神经根的任何变化，并进行一致性和相关性分析。
T2WI显示78条神经根受压，CE T1WI显示52例神经根强化。67条神经根在DW MRN上显示肿胀和高信号。共有42条神经根在CE T1WI和DW MRN序列上出现变化。DW MRN与CE T1WI以及DW MRN与T2WI之间观察到中度至高度一致性和中度正相关性（κ = 0.59 - 0.65，ρ = 0.600 - 0.653）。
使用前后向单向MPG的DW MRN有助于评估脊神经根的神经炎相关变化，并可作为一种能够补充或替代钆对比增强成像的序列。
