Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, United States.
Department of Microbiology, National Pirogov Memorial Medical University, Vinnytsia, Ukraine.
Euro Surveill. 2024 Jun;29(24). doi: 10.2807/1560-7917.ES.2024.29.24.2400259.
In 2003-2023, amid 5,436 isolates collected globally through the Multidrug-Resistant Organism Repository and Surveillance Network, 97 were ST19PAS, 34 of which carbapenem-resistant. Strains (n = 32) sampled after 2019 harboured either , , and/or . Phylogenetic analysis of the 97 isolates and 11 publicly available ST19 genomes revealed three sub-lineages of carbapenemase-producing isolates from mainly Ukraine and Georgia, including an epidemic clone carrying all three carbapenemase genes. Infection control and global surveillance of carbapenem-resistant remain important.
在 2003 年至 2023 年间，通过多药耐药菌库和监测网络在全球范围内收集了 5436 株分离株，其中 97 株为 ST19PAS，其中 34 株为碳青霉烯类耐药。2019 年后采样的菌株（n=32）携带 、 、和/或 。对 97 株分离株和 11 株公开的 ST19 基因组进行的系统发育分析显示，来自乌克兰和格鲁吉亚的产碳青霉烯酶分离株有三个亚系，包括一个携带所有三种碳青霉烯酶基因的流行克隆。对碳青霉烯类耐药的感染控制和全球监测仍然很重要。
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