Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK.
Obesity and Eating Disorders Clinic, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico.
Adv Neurobiol. 2024;35:357-380. doi: 10.1007/978-3-031-45493-6_18.
This third and final chapter in our trilogy introduces the clinical distinctions and phenotypical similarities between obesity and eating disorders. Research elaborating on the shared neurobiological substrates for obesity and eating disorders is discussed. We present an interprofessional model of treatment for both disordered eating and for obesity. Additionally, this chapter establishes the translational importance of research connecting endogenous opioid activity with both obesity and eating disorders, with an emphasis on clinical interventions. We conclude with a discussion of future directions for research.
这是我们三部曲的第三也是最后一章，介绍了肥胖症和饮食失调之间的临床差异和表型相似之处。讨论了阐述肥胖症和饮食失调共同神经生物学基础的研究。我们提出了一种针对饮食失调和肥胖症的跨专业治疗模式。此外，本章还确立了将内源性阿片活性与肥胖症和饮食失调联系起来的研究的转化重要性，重点是临床干预。最后，我们讨论了未来的研究方向。
