Rehabilitation Medicine Department, the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China.
Department of Acupuncture and Moxibustion, The First Affiliated Hospital of Ji'nan University, Guangzhou, Gungdong Province, China.
Medicine (Baltimore). 2024 Jun 14;103(24):e38436. doi: 10.1097/MD.0000000000038436.
Cerebral embolism presents a significant challenge for recovery of motor and neurological function. Early integrated rehabilitation therapy (EIRT) has been proposed as a beneficial approach, yet its efficacy requires thorough evaluation. This retrospective study, conducted from January 2020 to January 2023, involved 117 patient's post-cerebral embolism, divided into an EIRT group (n = 56) receiving EIRT and a control group (n = 61) receiving standard care. The Fugl-Meyer Assessment (FMA) and the National Institutes of Health Stroke Scale (NIHSS) were used to evaluate motor and neurological functions, while muscle strength was categorized from Level 0 (complete paralysis) to Level V (normal strength) to assess physical recovery. Eligibility centered on confirmed cerebral embolism diagnosis, timing of poststroke admission, and baseline functional status. The study adhered to strict ethical standards, with informed consent obtained from all participants. The EIRT group showed substantial improvements in both FMA and NIHSS scores compared to the control group, indicating better motor and neurological recovery. Significant differences were found in the posttreatment FMA (P < .01) and NIHSS scores (P < .01). Muscle strength analysis further confirmed the positive impact of EIRT with more patients in the EIRT group achieving higher levels of muscle strength at discharge. The study demonstrates the potential of EIRT to significantly improve motor and neurological outcomes for patient's post-cerebral embolism. The marked improvements in the observation group suggest that EIRT should be considered for broader application in stroke rehabilitation to enhance recovery and improve quality of life.
脑栓塞对运动和神经功能的恢复构成了重大挑战。早期综合康复治疗（EIRT）已被提出是一种有益的方法，但需要对其疗效进行全面评估。这项回顾性研究于 2020 年 1 月至 2023 年 1 月进行，涉及 117 名脑栓塞后患者，分为接受 EIRT 的 EIRT 组（n=56）和接受标准护理的对照组（n=61）。采用 Fugl-Meyer 评估（FMA）和美国国立卫生研究院卒中量表（NIHSS）评估运动和神经功能，同时将肌力分为 0 级（完全瘫痪）至 5 级（正常肌力）来评估身体恢复情况。入选标准为确诊脑栓塞、脑卒中后入院时间和基线功能状态。研究遵循严格的伦理标准，所有参与者均获得知情同意。与对照组相比，EIRT 组的 FMA 和 NIHSS 评分均有显著改善，表明运动和神经功能恢复更好。治疗后 FMA（P<.01）和 NIHSS 评分（P<.01）差异有统计学意义。肌力分析进一步证实了 EIRT 的积极影响，EIRT 组中有更多的患者在出院时达到更高的肌力水平。该研究表明，EIRT 可显著改善脑栓塞后患者的运动和神经功能结局。观察组的显著改善表明，EIRT 应在脑卒中康复中得到更广泛的应用，以促进康复并提高生活质量。
