Postgraduate Program in Food Science, Faculty of Food Engineering, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil; Institute of Agricultural Science, Postgraduate Program in Food and Health, University Federal of Minas Gerais (UFMG), Montes Claros, Minas Gerais, Brazil.
Postgraduate Program in Health Sciences, State University of Montes Claros (UNIMONTES), Montes Claros, Minas Gerais, Brazil.
Food Res Int. 2024 Aug;189:114570. doi: 10.1016/j.foodres.2024.114570. Epub 2024 May 27.
Edible insects are recognized as promising food sources due to their nutritional composition. Some species, such as Gryllus assimilis, contain proteins, lipids, and carbohydrates of high biological value, which regulate several metabolic functions, including the Renin-Angiotensin System (RAS). In this context, the present study aimed to assess the effects of dietary supplementation with whole Gryllus assimilis powder on the metabolism of malnourished mice. Thirty-two male Swiss mice were used and divided into four treatment groups. The groups were identified as (AIN93-M); AIN93-M + Gryllus assimilis diet (AIN93-M + GA); AIN93-M + Renutrition diet (AIN93-M + REN) and AIN93-M + Renutrition diet + Gryllus assimilis (AIN93-M + REN + GA). The results showed that whole Gryllus assimilis powder inclusion promotes recovery from protein-energy malnutrition, reduces adiposity, and improves glucose tolerance and insulin sensitivity. It also reduces total cholesterol, triglycerides, VLDL, and adipocyte area. We also observed a significant increase in the expression of RAS-related genes, such as ACE2 and MasR, followed by a reduction in Angiotensinogen and ACE. The main findings of the present study suggest the use of black cricket as a viable strategy for the prevention and treatment of protein-energy malnutrition, as well as the reduction of adiposity, and improvement of lipid and glycemic parameters, with antihypertensive potential.
食用昆虫因其营养成分而被认为是有前途的食物来源。一些物种，如东亚飞蝗，含有高生物价值的蛋白质、脂肪和碳水化合物，它们调节着多种代谢功能，包括肾素-血管紧张素系统（RAS）。在这种情况下，本研究旨在评估用整只东亚飞蝗粉补充饮食对营养不良小鼠代谢的影响。使用了 32 只雄性瑞士小鼠，并将它们分为四组处理。这些组分别被确定为（AIN93-M）；AIN93-M+东亚飞蝗饮食（AIN93-M+GA）；AIN93-M+Renutrition 饮食（AIN93-M+REN）和 AIN93-M+Renutrition 饮食+东亚飞蝗（AIN93-M+REN+GA）。结果表明，整只东亚飞蝗粉的添加促进了蛋白质-能量营养不良的恢复，减少了肥胖，改善了葡萄糖耐量和胰岛素敏感性。它还降低了总胆固醇、甘油三酯、VLDL 和脂肪细胞面积。我们还观察到 RAS 相关基因的表达显著增加，如 ACE2 和 MasR，随后 Angiotensinogen 和 ACE 减少。本研究的主要发现表明，使用黑蟋蟀作为预防和治疗蛋白质-能量营养不良、减少肥胖以及改善脂质和血糖参数的可行策略具有降压潜力。
