Hemifacial Spasm Research Group, Helsinki University Hospital, HUS Neurocenter, Helsinki, Uusimaa, Finland.
Department of Neurology, Helsinki University Hospital, Helsinki, Uusimaa, Finland.
Acta Neurochir (Wien). 2024 Jun 15;166(1):268. doi: 10.1007/s00701-024-06149-0.
Radiofrequency thermocoagulation (RFT) is a treatment used to relieve symptoms of cranial nerve disorders. The current study is the first to describe the results of hemifacial spasm (HFS) patients with a history of repeated RFT in the second-largest consecutive single-center patient series with long-term follow-up.
This retrospective study was conducted in the largest hospital district in Finland (Helsinki and Uusimaa). Consecutive HFS patients who had an RFT to treat HFS in the Hospital District of Helsinki and Uusimaa between 2009-2020 were included.
Eighteen patients with 53 RFTs were identified from the medical records. 11 (61 %) patients had repeated RFTs, and the mean number of RFTs per patient was 3.33 (3.29 SD). The mean follow-up was 5.54 years (7.5 SD). 12 (67 %) patients had had microvascular decompression (MVD) before RFT. Patients were satisfied with the results after 87 % of RFTs. Relief of the twitching of the face lasted 11.27 months (11.94 SD). All patients had postoperatively transient facial paresis. Postoperative paresis lasted a mean of 6.47 months (6.80 SD). The depth of paresis was postoperatively typically moderate (36.54 %, House Brackmann III). 23.08 % had mild paresis (House-Brackmann II), 23.08 % had moderately severe dysfunction (House-Brackmann IV), 9.62 % had severe dysfunction, and 7.69 % had total paralysis of the facial muscles (House-Brackmann VI). Duration of relief in the face twitching (p 0.002) and temperature at the final coagulation point (p 0.004) were statistically significant predictors of satisfaction with the RFT results.
RFT can be used to treat recurrences of HFS repeatedly. It provides symptom relief for around 11 months, lasting four times longer than with botulinum toxin injections. Patients are satisfied, although an RFT produces transient, sometimes even severe, facial paresis.
射频热凝(RFT)是一种用于缓解颅神经疾病症状的治疗方法。本研究首次描述了既往接受过 RFT 治疗的面肌痉挛(HFS)患者的结果,这是在第二大连续单中心患者系列中进行的,随访时间最长。
这项回顾性研究在芬兰(赫尔辛基和乌西玛)最大的医院区进行。在赫尔辛基和乌西玛医院区,纳入了 2009-2020 年间接受 RFT 治疗 HFS 的连续 HFS 患者。
从病历中确定了 18 名接受了 53 次 RFT 的患者。11 名(61%)患者接受了重复 RFT,每位患者的 RFT 次数平均为 3.33(3.29 SD)。平均随访时间为 5.54 年(7.5 SD)。12 名(67%)患者在 RFT 前曾接受微血管减压术(MVD)。87%的 RFT 后患者对结果满意。面部抽搐缓解持续 11.27 个月(11.94 SD)。所有患者术后均有短暂的面瘫。面瘫平均持续 6.47 个月(6.80 SD)。术后瘫痪程度通常为中度(36.54%,House Brackmann III)。23.08%为轻度瘫痪(House-Brackmann II),23.08%为中度功能障碍(House-Brackmann IV),9.62%为重度功能障碍,7.69%为面部肌肉完全瘫痪(House-Brackmann VI)。面部抽搐缓解时间(p<0.002)和最终凝固点温度(p<0.004)是 RFT 结果满意度的统计学显著预测因素。
RFT 可用于反复治疗 HFS 复发。它可以缓解症状约 11 个月,持续时间是肉毒毒素注射的四倍。患者对治疗结果满意,尽管 RFT 会导致短暂的,有时甚至严重的面瘫。