Nurminen Paula, Marjamaa Johan, Niemelä Mika, Sairanen Tiina
Hemifacial Spasm Research Group, Meilahti Hospital, HUS Neurocenter Haartmaninkatu 4, 00029 Helsinki, Finland.
Hemifacial Spasm Research Group, Meilahti Hospital, HUS Neurocenter Haartmaninkatu 4, 00029 Helsinki, Finland; Department of Neurosurgery, Töölö Hospital, HUS Neurocenter, Topeliuksenkatu 5, 00260 Helsinki, Finland.
J Neurol Sci. 2023 Mar 15;446:120587. doi: 10.1016/j.jns.2023.120587. Epub 2023 Feb 12.
Hemifacial spasm (HFS) is a movement disorder of facial muscles innervated by the facial nerve. This condition often demands regular utilization of healthcare resources. However, knowledge of the incidence and prevalence of this condition is based on scarce studies. This research aimed to identify the incidence and prevalence of HFS in Finland's largest hospital district.
This retrospective study was conducted in the largest hospital district in Finland (Helsinki and Uusimaa). The study included consecutive HFS patients who visited the departments of Neurology and Neurosurgery in the Hospital District of Helsinki and Uusimaa between 2014 and 2019. The demographics included sex, side of the spasm, treatment allocations, duration of symptoms before diagnosis, and age at the time of diagnosis.
279 patients were identified from the medical records. 62% of patients were women and had left-sided spasms. The crude mean incidence among women was almost double that of men (1.86 vs. 0.94). The highest crude mean annual incidence among men was in the age group 60-79 years, while among women, it peaked in the age group 80 years and over. The mean annual age-standardized incidence of HFS was 1.53, 1.94 in women, and 1.05 in men. The mean age-standardized yearly prevalence was 10.62, 11.62 among women, and 9.31 among men. The annual age-standardized prevalence of HFS increased steadily from 2014 to 2019.
The incidence and prevalence of women outnumbered men. HFS is typically left-sided. The HFS incidence peaked after 80 years in women and men aged 60-79 years.
半面痉挛（HFS）是一种由面神经支配的面部肌肉运动障碍。这种疾病常常需要定期使用医疗资源。然而，关于这种疾病的发病率和患病率的了解基于稀少的研究。本研究旨在确定芬兰最大医院区半面痉挛的发病率和患病率。
这项回顾性研究在芬兰最大的医院区（赫尔辛基和新地区）进行。研究纳入了2014年至2019年间在赫尔辛基和新地区医院区的神经内科和神经外科就诊的连续性半面痉挛患者。人口统计学数据包括性别、痉挛侧、治疗分配、诊断前症状持续时间以及诊断时的年龄。
从病历中识别出279例患者。62%的患者为女性，且痉挛发生在左侧。女性的粗平均发病率几乎是男性的两倍（1.86对0.94）。男性中粗平均年发病率最高的年龄组为60 - 79岁，而女性中则在80岁及以上年龄组达到峰值。半面痉挛的平均年龄标准化年发病率为1.53，女性为1.94，男性为1.05。平均年龄标准化年患病率为10.62，女性为11.62，男性为9.31。2014年至2019年期间，半面痉挛的年龄标准化年患病率稳步上升。
女性的发病率和患病率高于男性。半面痉挛通常发生在左侧。女性半面痉挛发病率在80岁后达到峰值，男性在60 - 79岁达到峰值。
