Center of Allergy and Immunology, Santa Fe, Argentina.
Department of Pulmonology, Medical Faculty, Celal Bayar University, Manisa, Turkey.
Asian Pac J Allergy Immunol. 2024 Sep;42(3):207-221. doi: 10.12932/AP-181023-1710.
Several studies suggest that patients often under-estimate their asthma symptoms and over-estimate their level of asthma control, potentially putting them at risk of undertreatment with inhaled corticosteroids.
To determine the association and correlation between patient symptom perception and asthma control.
A rapid literature review comprising searches in MEDLINE, Embase and Cochrane Library identified English language articles published between 2011-2021 that included a statistical measure of the association or correlation between perceptions of symptoms and asthma control in patients with asthma (adults and/or children). [PROSPERO CRD42021230152]. The Joanna Briggs Institute (JBI) instrument was used for study quality appraisal.
Of 22 identified studies, nine presented association data and 13 reported correlation analyses. Eight of nine association studies showed a discordance between patients perceived symptoms and level of asthma control or lung function; among these, patients more frequently overestimated their asthma control than they underestimated their asthma control. Of 10 studies reporting correlation coefficients, all reported a statistically significant correlation between increased symptoms and worse asthma control; however, the strength of the correlation was shown to be only weak or moderate in most studies (coefficients numerically ranged from 0.12 to 0.74).
Many patients with asthma tend to overestimate their level of asthma control. Although more frequent or worse symptoms were shown to be statistically significantly correlated with worsening asthma control, there was wide variation in correlation strengths, most showing weak or moderate correlations. Research to further understand the reasons for patient symptom misperceptions are warranted.
多项研究表明，患者常常低估自己的哮喘症状，高估自己的哮喘控制水平，这可能使他们面临吸入性皮质类固醇治疗不足的风险。
确定患者症状感知与哮喘控制之间的关联和相关性。
快速文献综述包括在 MEDLINE、Embase 和 Cochrane Library 中进行的搜索，确定了 2011 年至 2021 年间发表的英语文章，这些文章包括了哮喘患者（成人和/或儿童）中症状感知与哮喘控制之间关联或相关性的统计测量。[PROSPERO CRD42021230152]。使用 Joanna Briggs 研究所（JBI）工具进行研究质量评估。
在 22 项已确定的研究中，有 9 项呈现了关联数据，13 项报告了相关分析。在 9 项关联研究中，有 8 项显示出患者感知的症状与哮喘控制或肺功能水平之间存在差异；其中，患者更频繁地高估自己的哮喘控制水平，而不是低估。在报告相关系数的 10 项研究中，所有研究都报告了症状增加与哮喘控制恶化之间存在统计学显著相关性；然而，大多数研究显示相关性强度较弱或中等（系数数值范围从 0.12 到 0.74）。
许多哮喘患者往往高估自己的哮喘控制水平。虽然更频繁或更严重的症状与哮喘控制恶化呈统计学显著相关，但相关性强度存在很大差异，大多数显示弱或中等相关性。有必要进行进一步研究，以更好地理解患者症状误解的原因。
