Faculty of Medicine and Dentistry, University of Plymouth, John Bull Building, Plymouth Science Park, Plymouth, UK.
Br J Anaesth. 2024 Jul;133(1):16-18. doi: 10.1016/j.bja.2024.04.005. Epub 2024 May 16.
Anaesthesia induced with remimazolam and a fentanyl-series opioid can be reversed with flumazenil and naloxone. Concomitant paralysis with rocuronium can facilitate tracheal intubation whilst being reversible with sugammadex. Together, this combination might offer full reversibility of a 'routine' or a 'rapid-sequence' induction anaesthesia. Whether this is useful, or even safe, requires careful evaluation.
以雷米唑仑和芬太尼类阿片类药物诱导麻醉,可用氟马西尼和纳洛酮逆转。同时使用罗库溴铵进行麻痹可便于气管插管,并用 sugammadex 逆转。这种联合用药可能提供“常规”或“快速序贯”诱导麻醉的完全逆转。这种方法是否有用,甚至是否安全,需要仔细评估。