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具有智力和/或发育障碍的个体群体之家中 COVID-19 感染和住院的预测因素。

Predictors of COVID-19 infection and hospitalization in group homes for individuals with intellectual and/or developmental disabilities.

机构信息

Massachusetts General Hospital, Mongan Institute, 100 Cambridge St, Suite 1600, Boston, MA, 02114, USA; Massachusetts General Hospital, Department of Medicine, 55 Fruit St, Gray 7-730, Boston, MA, 02114, USA; Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA.

Massachusetts General Hospital, Mongan Institute, 100 Cambridge St, Suite 1600, Boston, MA, 02114, USA; Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA.

出版信息

Disabil Health J. 2024 Oct;17(4):101645. doi: 10.1016/j.dhjo.2024.101645. Epub 2024 Jun 5.

Abstract

BACKGROUND

More than seven million people with intellectual and/or developmental disabilities (ID/DD) live in the US and may face an elevated risk for COVID-19.

OBJECTIVE

To identify correlates of COVID-19 and related hospitalizations among people with ID/DD in group homes in Massachusetts.

METHODS

We collected data during March 1, 2020-June 30, 2020 (wave 1) and July 1, 2020-March 31, 2021 (wave 2) from the Massachusetts Department of Public Health and six organizations administering 206 group homes for 1035 residents with ID/DD. The main outcomes were COVID-19 infections and related hospitalizations. We fit multilevel Cox proportional hazards models to estimate associations with observed predictors and assess contextual home- and organizational-level effects.

RESULTS

Compared with Massachusetts residents, group home residents had a higher age-adjusted rate of COVID-19 in wave 1 (incidence rate ratio [IRR], 12.06; 95 % confidence interval [CI], 10.51-13.84) and wave 2 (IRR, 2.47; 95 % CI, 2.12-2.88) and a higher age-adjusted rate of COVID-19 hospitalizations in wave 1 (IRR, 17.64; 95 % CI, 12.59-24.70) and wave 2 (IRR, 4.95; 95 % CI, 3.23-7.60). COVID-19 infections and hospitalizations were more likely among residents aged 65+ and in group homes with 6+ resident beds and recent infection among staff and residents.

CONCLUSIONS

Aggressive efforts to decrease resident density, staff-to-resident ratios, and staff infections through efforts such as vaccination, in addition to ongoing access to personal protective equipment and COVID-19 testing, may reduce COVID-19 and related hospitalizations in people with ID/DD living in group homes.

摘要

背景

美国有超过 700 万患有智力和/或发育障碍 (ID/DD) 的人,他们可能面临更高的 COVID-19 风险。

目的

确定马萨诸塞州群体家庭中 ID/DD 患者 COVID-19 感染及相关住院的相关因素。

方法

我们于 2020 年 3 月 1 日至 6 月 30 日(第 1 波)和 2020 年 7 月 1 日至 2021 年 3 月 31 日(第 2 波)期间从马萨诸塞州公共卫生部和六个管理 206 个 ID/DD 居民群体家庭的组织收集数据。主要结局为 COVID-19 感染和相关住院。我们拟合多水平 Cox 比例风险模型,以估计与观察到的预测因素的关联,并评估家庭和组织层面的背景效应。

结果

与马萨诸塞州居民相比,群体家庭居民在第 1 波(调整年龄后的发病率比 [IRR],12.06;95%置信区间 [CI],10.51-13.84)和第 2 波(IRR,2.47;95%CI,2.12-2.88)的 COVID-19 感染率更高,第 1 波(IRR,17.64;95%CI,12.59-24.70)和第 2 波(IRR,4.95;95%CI,3.23-7.60)的 COVID-19 住院率也更高。年龄在 65 岁及以上的居民以及居民床位在 6 张及以上的群体家庭以及工作人员和居民最近感染的居民中,COVID-19 感染和住院的可能性更大。

结论

通过接种疫苗等努力降低居民密度、工作人员与居民的比例以及工作人员感染,以及持续获得个人防护设备和 COVID-19 检测,可能会降低居住在群体家庭中的 ID/DD 患者的 COVID-19 和相关住院率。

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