[朗格汉斯细胞——其结构、功能及病理作用]
[Langerhans cells--their structure, function and pathological role].
作者信息
Persina I S
出版信息
Arkh Patol. 1985;47(2):86-93.
PMID:3888151
Abstract
Data on the structure and function of Langerhans' cells (LC) are presented. LC are defined as dendritic cells of the epidermis and mucous membrane epithelium having the mesenchymal origin and relating to the antigen-representing macrophages. Morphological, enzymatic and antigenic LC markers are characterized. The crucial role of LC in the development of the skin delayed type hypersensitivity is shown: contact hypersensitivity, specific inflammation, transplant rejection, neoplastic process.
摘要
本文介绍了朗格汉斯细胞（LC）的结构和功能数据。LC被定义为表皮和黏膜上皮的树突状细胞，起源于间充质，与抗原呈递巨噬细胞相关。对LC的形态学、酶学和抗原性标志物进行了表征。研究表明LC在皮肤迟发型超敏反应的发生发展中起关键作用：接触性超敏反应、特异性炎症、移植排斥反应、肿瘤形成过程。
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