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MMP-9 deficiency accelerates the progress of periodontitis.

作者信息

Wan Chun-Yan, Yin Yixin, Li Xiaoyan, Liu Meng Meng, Goldman Graham, Wu Li-An, Wang Feng, Luo Dao-Shu, Chen Zhuo, Xu Wen-An, Chen Stephen, MacDougall Mary, Lindsey Merry L, Chen Zhi, Chen Shuo

机构信息

Department of Endodontics, The Affiliated Hospital of Qingdao University, School of Stomatology, Qingdao University, Qingdao, Shandong 266003, China.

Department of Developmental Dentistry, School of Dentistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

出版信息

Genes Dis. 2024 Jan 28;11(5):101231. doi: 10.1016/j.gendis.2024.101231. eCollection 2024 Sep.

DOI:10.1016/j.gendis.2024.101231
PMID:38882016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11176640/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/d5e447100e06/figs5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/702ba97125c5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/216af6139677/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/1c92ff223b21/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/3fb94e2670b8/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/3128ba2562d1/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/d5e447100e06/figs5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/702ba97125c5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/216af6139677/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/1c92ff223b21/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/3fb94e2670b8/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/3128ba2562d1/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3793/11176640/d5e447100e06/figs5.jpg

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1
MMP-9 deficiency accelerates the progress of periodontitis.基质金属蛋白酶-9缺乏会加速牙周炎的进展。
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本文引用的文献

1
Matrix Metalloproteinase-3 but Not Matrix Metalloproteinase-9, Implicated in the Manifestation of Chronic Periodontitis.基质金属蛋白酶-3而非基质金属蛋白酶-9与慢性牙周炎的表现有关。
Rep Biochem Mol Biol. 2023 Jan;11(4):656-662. doi: 10.52547/rbmb.11.4.656.
2
Inflamm-Aging-Related Cytokines of IL-17 and IFN- Accelerate Osteoclastogenesis and Periodontal Destruction.炎性衰老相关细胞因子白介素-17 和干扰素-γ 加速破骨细胞形成和牙周破坏。
J Immunol Res. 2021 Aug 4;2021:9919024. doi: 10.1155/2021/9919024. eCollection 2021.
3
Periodontal Disease, Tooth Loss, and Cancer Risk.
牙周病、牙齿脱落与癌症风险。
Epidemiol Rev. 2017 Jan 1;39(1):49-58. doi: 10.1093/epirev/mxx006.
4
Prenatal course of metaphyseal anadysplasia associated with homozygous mutation in MMP9 identified by exome sequencing.通过外显子组测序鉴定出 MMP9 基因纯合突变导致的干骺端发育不良的产前病程。
Clin Genet. 2017 Dec;92(6):645-648. doi: 10.1111/cge.13020. Epub 2017 Aug 3.
5
MMP9 deficiency increased the size of experimentally induced apical periodontitis.基质金属蛋白酶9缺乏会增大实验性诱导的根尖周炎的面积。
J Endod. 2014 May;40(5):658-64. doi: 10.1016/j.joen.2014.01.003. Epub 2014 Mar 18.