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用于治疗大型牙源性角化囊肿的两阶段手术方案

2-Staged Surgical Protocol for Management of Large Odontogenic Keratocyst.

作者信息

Malhotra Prachur, Sinha Debasish, Chandalia Saurabh, Shah Deep, Mulay Mrudula, Shah Kreena

机构信息

Department of Oral and Maxillofacial Surgery, K M Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.

出版信息

J Pharm Bioallied Sci. 2024 Apr;16(Suppl 2):S1888-S1891. doi: 10.4103/jpbs.jpbs_1210_23. Epub 2024 Apr 16.

Abstract

The World Health Organisation classification and the treatment protocol for the odontogenic keratocyst (OKC), previously referred to as the keratocystic odontogenic tumour, were examined based on a study of the literature. Because not all OKCs have an identifiable protein patched homolog mutation, the idea of changing the management protocol for OKC in response to this shift in tumour category was met with scepticism and was not widely adopted. This study's objective was to outline a successful management plan for an odontogenic keratocyst in a patient who was 23 years old. The procedure for therapy involved marsupialisation, which was followed by enucleation, peripheral osteotomy, and the injection of 5 FFU. Following a 2-year observation period (clinical and radiological monitoring), it was found that bone regeneration was normal and there was no sign of a recurrence.

摘要

基于文献研究,对世界卫生组织关于牙源性角化囊肿(OKC,以前称为角化囊性牙源性肿瘤)的分类和治疗方案进行了审视。由于并非所有牙源性角化囊肿都有可识别的蛋白patched同源突变,因此,针对肿瘤分类的这种变化而改变牙源性角化囊肿管理方案的想法遭到了质疑,并未被广泛采用。本研究的目的是为一名23岁患者的牙源性角化囊肿制定一个成功的管理计划。治疗程序包括袋形术,随后是摘除术、周边截骨术和注射5个氟尿嘧啶单位。经过2年的观察期(临床和放射学监测),发现骨再生正常,没有复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8d3/11174286/544eb03282f1/JPBS-16-1888-g001.jpg

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