Principal Researcher, Maxillofacial Department, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Oct;116(4):e271-6. doi: 10.1016/j.oooo.2011.12.028. Epub 2012 Jul 6.
The objective of this study was to evaluate the most up-to-date treatment modalities and respective recurrence rates for keratocystic odontogenic tumor (KCOT).
A systematic review of the literature from 1999 to 2010 was undertaken examining treatment and recurrence rates for KCOT. Four inclusion criteria were defined for articles to then be analyzed against 8 standards.
Of the 2736 published articles, 8 met the inclusion criteria. When merging the data, enucleation and enucleation with adjunctive measures (other than Carnoy's solution) had recurrence rates of 25.6% and 30.3%, respectively. Marsupialization with adjunctive measures produced a recurrence rate of 15.8%, whereas enucleation with Carnoy's solution presented a recurrence rate of 7.9%. Only one resection case had recurrence (6.3%).
The enucleation technique with the use of adjunctive procedures (other than Carnoy's solution) provides a higher recurrence rate than any other treatment modality.
本研究旨在评估牙源性角化囊性瘤（KCOT）的最新治疗方法及其复发率。
对 1999 年至 2010 年的文献进行系统回顾，研究 KCOT 的治疗和复发率。为了进行分析，确定了 4 条纳入标准，并针对 8 条标准进行评估。
在 2736 篇已发表的文章中，有 8 篇符合纳入标准。合并数据后，剜除术和剜除术联合辅助措施（除 Carnoy 液外）的复发率分别为 25.6%和 30.3%。袋形手术联合辅助措施的复发率为 15.8%，而 Carnoy 液联合剜除术的复发率为 7.9%。仅 1 例切除病例复发（6.3%）。
剜除术联合辅助措施（除 Carnoy 液外）的治疗方法比其他任何治疗方法的复发率都高。
