Senthil Rethesh, Sivanand Nikhil, Karthikeyan Padmanabhan
Department of ENT, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pillaiyarkuppam, Pondicherry India.
Indian J Otolaryngol Head Neck Surg. 2024 Jun;76(3):2351-2354. doi: 10.1007/s12070-024-04483-4. Epub 2024 Jan 23.
To find the prevalence of hearing loss in children born to mothers who had COVID-19 infection during pregnancy.
This was a prospective observational study conducted on 1960 babies born to mothers who were COVID positive during their pregnancy .All children born to RTPCR positive COVID-19 pregnant women were included in the study and babies who had any other risk factor for neonatal SNHL were excluded from the study. All the babies were subjected to OAE, and if it came pass, the test was repeated 2 weeks later. Those patients with repeat OAE also as refer were subjected to Brainstem Evoked Response Audiometry and findings correlated.
The study included 1960 neonates who were subjected to neonatal hearing screening by OAE. There were 1020 males (52.04%) and 940(47.96%) females and 80 cases of consanguinity. Fifty babies were excluded due to comorbidities. In the initial OAE test 380 neonates failed (19.9%) following which BERA was done and ten patients was found to Sensorineural hearing loss.
The prevalence of hearing loss in our study on babies born to mothers with COVID-19 infection during pregnancy is 0.005. Although these primary results from our study does not indicate any immediate effect of SARS-COV-2 maternal infection on neonatal hearing. More children need to be tested and followed up over an extended period of time to detect any possible delayed auditory effects. Those patients who were identified to have hearing loss in our study will have to be on long term follow-up as we see long terms effects on cognition, memory, heart health, etc. in COVID survivors.
Level 1.
探讨孕期感染新冠病毒的母亲所生儿童的听力损失患病率。
这是一项前瞻性观察性研究，对1960名母亲在孕期新冠病毒检测呈阳性的婴儿进行研究。所有RTPCR检测呈阳性的新冠病毒感染孕妇所生儿童均纳入研究，排除有任何其他新生儿感音神经性听力损失风险因素的婴儿。所有婴儿均接受耳声发射（OAE）检测，若检测通过，则在2周后重复检测。那些重复OAE检测仍为转诊的患者接受脑干听觉诱发电位（BERA）检测，并对结果进行相关性分析。
该研究纳入了1960名接受OAE新生儿听力筛查的新生儿。其中男性1020名（52.04%），女性940名（47.96%），近亲结婚80例。50名婴儿因合并症被排除。在初次OAE检测中，380名新生儿未通过（19.9%），随后进行了BERA检测，发现10名患者有感音神经性听力损失。
在我们的研究中，孕期感染新冠病毒的母亲所生婴儿的听力损失患病率为0.005。尽管我们研究的这些初步结果并未表明母亲感染SARS-CoV-2对新生儿听力有任何即时影响。需要对更多儿童进行更长时间的检测和随访，以发现任何可能的延迟听觉影响。在我们的研究中被确定有听力损失的患者将必须进行长期随访，因为我们在新冠病毒幸存者中看到了对认知、记忆、心脏健康等方面的长期影响。
1级。
