Fang Yu, Lin Ching-Kai, Yao Zong-Han, Fan Hung-Jen, Cheng Ya-Jung
Department of Anesthesiology, National Taiwan University Hospital, Taipei.
Department of Medicine, National Taiwan University Cancer Center, Taipei.
J Thorac Dis. 2024 May 31;16(5):3042-3050. doi: 10.21037/jtd-23-1935. Epub 2024 May 28.
Anesthesia remains challenging for bronchoscopic tracheobronchial surgeries (BTS) involving surgical manipulations for central airway obstruction within shared airways. To provide complete airway use through intervention with spontaneous breathing without endotracheal tubes, monitored non-intubated anesthesia has been successfully applied with electroencephalogram-derived monitored total intravenous anesthesia. This study evaluated the feasibility and the outcomes of BTS with monitored non-intubated anesthesia. The factors associated with desaturation and complications were also analyzed.
Data from patients receiving non-intubated BTS performed between October 2019 and August 2022 were retrospectively collected. Intraoperative results and postoperative outcomes were analyzed.
Data of 92 patients were collected. Supraglottic airways devices and high-flow nasal oxygen were used in 68 and 24 patients respectively. Surgery was successfully completed in 87 patients (94.6%), whereas three patients required conversion to intubation because of substantial bleeding. In total, 11% of patients experienced desaturation [oxygen saturation (SpO) <90%] for an average of 9 minutes. Unexpected admission to the intensive care unit (ICU) occurred in 12.2% (5/41) of patients from outpatient department and 7.8% (4/51) of hospitalization settings because of high-grade surgical bleeding. With comparable desaturation incidence, tracheal surgery had significantly longer desaturation times (14.5±6.9 min) than bronchial surgeries (5.8±2.6 min) did.
Monitored non-intubated anesthesia with spontaneous breathing is feasible for BTS, with high success rate, few complications, and rapid recovery. High-grade bleeding remains the most unpredictable risk for intraoperative desaturation and postoperative ICU admission, especially in tracheal obstruction cases.
对于涉及共享气道内中央气道梗阻手术操作的支气管镜气管支气管手术(BTS),麻醉仍然具有挑战性。为了在不使用气管插管的情况下通过干预自主呼吸实现气道的完全使用,基于脑电图监测的全静脉麻醉已成功应用于监测下非插管麻醉。本研究评估了监测下非插管麻醉用于BTS的可行性和结果。还分析了与血氧饱和度降低和并发症相关的因素。
回顾性收集2019年10月至2022年8月期间接受非插管BTS患者的数据。分析术中结果和术后结局。
收集了92例患者的数据。分别有68例和24例患者使用了声门上气道装置和高流量鼻导管吸氧。87例患者(94.6%)手术成功完成,而3例患者因大量出血需要转为插管。共有11%的患者出现血氧饱和度降低[血氧饱和度(SpO)<90%],平均持续9分钟。由于手术大出血,门诊患者中有12.2%(5/41)、住院患者中有7.8%(4/51)意外入住重症监护病房(ICU)。在血氧饱和度降低发生率相当的情况下,气管手术的血氧饱和度降低时间(14.5±6.9分钟)明显长于支气管手术(5.8±2.6分钟)。
对于BTS,自主呼吸的监测下非插管麻醉是可行的,成功率高,并发症少,恢复快。大出血仍然是术中血氧饱和度降低和术后入住ICU最不可预测的风险,尤其是在气管梗阻病例中。