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尼日利亚东北部境内流离失所者中的坏疽性口炎疾病:一项回顾性描述性研究。

Noma disease among internally displaced persons in Northeast Nigeria: a retrospective descriptive study.

作者信息

Abdullahi Mohammed A S, Balarabe Muhammad R, Tyndall Jennifer A, Alele Faith O, Habib Abdulrazaq G, Adegboye Oyelola A

机构信息

Department of Oral and Maxillofacial Surgery, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

出版信息

Ther Adv Infect Dis. 2024 Jun 13;11:20499361241261269. doi: 10.1177/20499361241261269. eCollection 2024 Jan-Dec.

Abstract

BACKGROUND

Recently recognized by the World Health Organization as a neglected tropical disease, Noma, an acute and destructive gangrenous disease affecting the gums and facial structures within the oral cavity, has a high mortality rate if untreated.

OBJECTIVES

To investigate the prevalence and impact of Noma among internally displaced populations in Northeastern Nigeria.

DESIGN

A retrospective study.

METHODS

This retrospective study investigates the prevalence and impact of Noma among internally displaced populations in Northeastern Nigeria. Noma is endemic in Northern Nigeria, Africa, and its occurrence has been linked to extreme poverty, malnutrition, poor hygiene, and inadequate healthcare - conditions exacerbated by the ongoing Boko Haram conflict.

RESULTS

The retrospective descriptive cross-sectional analysis of 17 cases reveals a median age of 8 years, with most of the patients being children who suffer significant social stigmas, such as difficulties in speaking, eating, and social integration, including reduced school attendance and marital prospects.

CONCLUSION

The study highlights the urgent need for comprehensive research into the etiology of Noma and its socio-economic impact. It emphasizes the necessity for early and effective intervention strategies, particularly in conflict-stricken areas with limited healthcare access.

摘要

背景

坏疽性口炎是一种影响口腔内牙龈和面部结构的急性破坏性坏疽性疾病,最近被世界卫生组织确认为一种被忽视的热带病,若不治疗,死亡率很高。

目的

调查尼日利亚东北部境内流离失所人群中坏疽性口炎的患病率及其影响。

设计

一项回顾性研究。

方法

这项回顾性研究调查了尼日利亚东北部境内流离失所人群中坏疽性口炎的患病率及其影响。坏疽性口炎在非洲尼日利亚北部为地方病,其发生与极端贫困、营养不良、卫生条件差以及医疗保健不足有关,而博科圣地冲突使这些情况更加恶化。

结果

对17例病例的回顾性描述性横断面分析显示,中位年龄为8岁,大多数患者为儿童,他们遭受严重的社会耻辱,如说话、进食困难以及社会融入问题,包括上学出勤率降低和婚姻前景受限。

结论

该研究突出表明迫切需要对坏疽性口炎的病因及其社会经济影响进行全面研究。它强调了早期和有效干预策略的必要性,特别是在医疗保健机会有限的冲突地区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdbe/11177724/f49316951193/10.1177_20499361241261269-fig1.jpg

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